Sign In
New User? Register
carersupportindianow
? Already a member? Sign in to Yahoo!

Yahoo! Groups Tips

Did you know...
You can search the group for older messages.

Messages

  Messages Help
Advanced
Messages 95 - 124 of 127   Newest  |  < Newer  |  Older >  |  Oldest
Messages: Show Message Summaries   (Group by Topic) Sort by Date v  
#124 From: Ashutosh Prabhu Dessai <ashutosh.prabhudessai@...>
Date:: Sat May 9, 2009 3:51 am
Subject:: effects of Abuse
ashutos2
Offline Offline
Send Email Send Email
 
Bullied Kids More Likely to Become Psychotic Preteens

Janis Kelly
http://www.medscape.com/viewarticle/702560?src=mpnews&spon=12&uac=101660BT

May 8, 2009 — Children who are bullied are more likely to develop
psychotic symptoms in early adolescence — and there is a dose effect,
with repeated bullying associated with greater risk.

In the first prospective study to examine the relationship between
childhood bullying and psychotic symptoms in early adolescence,
investigators at the University of Warwick, in Coventry, the United
Kingdom, found the risk for psychotic symptoms nearly doubled among
children who were victims of bullying at age 8 or 10 years,
independent of other psychiatric illness, family adversity, or the
child's IQ, and increased nearly 4-fold when victimization was chronic
or severe.

Study coauthor Dieter Wolke, PhD, told Medscape Psychiatry the
findings have clear clinical implications.

"If children present with physical or mental health problems, also
explore their peer relationships. Being victimized, in particular
chronically or severely, can make you ill," Dr. Wolke, told Medscape
Psychiatry.

The study is published in the May issue of Archives of General Psychiatry.

Significant Dose Effect

The researchers studied 6437 individuals in early adolescence (average
age, 12.9 years) who were part of the Avon Longitudinal Study of
Parents and Children (ALSPAC). Parents had completed regular mailed
questionnaires about their child's health and development since birth,
and the children underwent yearly physical and psychological
assessments from the age of 7 years.

At each visit, trained interviewers rated the children on whether they
had experienced psychotic symptoms, including hallucinations,
delusions, or thought disorders, during the previous 6 months.

Children, parents, and teachers also reported on whether the child had
experienced peer victimization, defined as negative actions by 1 of
more other students with the intention to hurt.

The researchers categorized 46.2% of participants as victims and 53.8%
as not victimized at either age 8 or 10 years. Dr. Wolke pointed out
that this includes being victimized at any time in childhood, not just
during the year in question.

At age 12.9, 13.7% of subjects had broad psychosislike symptoms with 1
or more symptoms suspected or definitely present; 11.5% had
intermediate symptoms with 1 or more symptoms suspected or present at
times other than going to sleep, waking from sleep, fever, or after
substance use; and 5.6% had 1 or more symptoms definitely present.

The odds ratio for psychotic symptoms was 1.94 among victims of
bullying at ages 8 and/or 10 years and jumped to 4.60 for repeated or
severe victimization.

Victims Often Less Socially Skilled

Dr. Wolke said it is doubtful that being a target of peer
victimization was the result rather than the cause of an underlying
predisposition to psychotic symptoms.

"This is the issue of reverse causality," Dr. Wolke said. "We are
fairly certain that this is not the case, as victimization reported by
mothers from 4 years onward also related to psychotic symptoms. Also,
it is not possible to measure psychotic symptoms before 8 years —
believing in Santa Claus or fairies is not a delusion but part of
appropriate development until that age."

"However," Dr. Wolke added, "we know victims show a reaction to
bullying more often — by crying for example — are less socially
skilled, and have no or few friends who can protect them. Thus, while
the children may not have had psychotic symptoms, they may be socially
awkward and were more likely to become targets. However, monozygotic
twin studies that are discordant for bullying show that the victimized
twin is more likely to develop depression and behavioral symptoms."

The researchers suggest further research is needed to sort out whether
repeated victimization experiences alter cognitive and affective
processing or reprogram stress response or whether psychotic symptoms
are more likely due to genetic predisposition.

"Social victimization by peers is a severe stress. It may lead to
reprogramming of the hypothalamic pituitary adrenal axis or a
different cognitive style, both found in those with psychosis. It may
be more severe in those with genetic susceptibility. However, these
are speculations that require more research,” Dr. Wolke said.

"A major implication is that chronic or severe peer victimization has
nontrivial, adverse, long-term consequences. Reduction of peer
victimization and of the resulting stress caused to victims could be a
worthwhile target for prevention and early intervention efforts for
common mental health problems and psychosis," the authors conclude.

Cause and Effect Not Demonstrated

David Fassler, MD, from the University of Vermont College of Medicine,
in Burlington, told Medscape Psychiatry that bullying is a common
experience for many young people.

"Surveys indicate that over half of all children are bullied at some
time during their school years, and at least 10% are bullied on a
regular basis,” Dr. Fassler said.

According to Dr. Fassler, previous research suggests bullying may
increase the risk of developing psychiatric disorders such as
schizophrenia or depression later in life. In this regard, the results
of the current study are consistent with previous reports and
demonstrate that children who are bullied during childhood are more
likely to show "psychoticlike" symptoms by early adolescence.

"Due to the design of the study, the authors can't actually prove that
these symptoms are a direct result of the bullying. However, they do
demonstrate a significant association," said Dr. Fassler. He warned
that the results of this study should be interpreted with caution due
to a number of methodological issues.

"For example, the authors experienced a significant dropout rate over
the course of the study. They were ultimately able to follow less than
half their original sample. In addition, they didn't have access to
baseline data on 'psychoticlike' symptoms for the children. However,
despite these limitations, the article represents a useful addition to
the literature on bullying.

"Hopefully, subsequent studies will help us identify kids who are
particularly vulnerable, so we can intervene as early as possible to
minimize the risk of lasting emotional consequences," Dr. Fassler
said.

The UK Medical Research Council, the Wellcome Trust, and the
University of Bristol provide core support for ALSPAC. This study was
funded by a grant from the Wellcome Trust. The authors report no
conflicts of interest.

Arch Gen Psychiatry. 2009;66: 527-536. Abstract


------------------------------------

Join IndianPsychiatrists for a pleasant e-experience!Yahoo! Groups Links

#123 From: Ashutosh Prabhu Dessai <ashutosh.prabhudessai@...>
Date:: Sat Apr 25, 2009 7:50 am
Subject:: The Soloist
ashutos2
Offline Offline
Send Email Send Email
 
A touching account of a person with schizophrenia and his family's
struggle also expalining
role of executive functioning in the condition

pl see link for photos and movie review
http://edition.cnn.com/2009/HEALTH/04/24/schizophrenia.soloist.brain/index.html


ad


Teen tries to quiet the voices caused by schizophrenia

By Madison Park
CNN


(CNN) -- The intrusive voices popped into William "Bill" Garrett's
head. "They're coming for you," the voices told the 18-year-old. "Find
somewhere to hide; they're going to get you."


Jennifer Ayers-Moore plays an air violin next to her older brother,
Nathaniel Ayers, in San Diego, California.
  2 of 3  They told the Johns Hopkins University freshman that his
father had poisoned the family dog, his sister had injected crystal
methamphetamine into his pet lizard and his grandmother had put human
body parts into his food.

As schizophrenia took hold, the Maryland teenager became lost within
his own mind and had to leave college after winning a full, four-year
scholarship.

Garrett's experience echoes the teenage years of Nathaniel Ayers, a
promising string bass player whose musical training at the Juilliard
School was cut short by schizophrenia, a brain disorder that blurs a
person's ability to distinguish between reality and delusions.

Ayers became homeless and played Beethoven pieces on a broken violin
in the streets of Los Angeles, California. His struggles with
schizophrenia and his friendship with a Los Angeles Times columnist
inspired the movie "The Soloist," which releases Friday.

His sister, Jennifer Ayers-Moore, hopes the movie will raise awareness
about schizophrenia and has established the Nathaniel Anthony Ayers
Foundation for the artistically gifted mentally ill.

"I know there are thousands of Nathaniels, and they deserve a chance,
too," said Ayers-Moore, an Atlanta-based social worker.

Teen interrupted

Schizophrenia is the result of disrupted brain development. Males
typically get symptoms during their teens or early 20s, as Ayers and
Garrett did.

"It's a critical time for the brain," said Dr. Jon McClellan, the
medical director of the Child Study and Treatment Center at Seattle
Children's Hospital. "It's the CEO part of the brain that pays
attention, makes decisions and filters. The prefrontal cortex, that's
the last area of the brain to develop. As that area comes online,
that's when the illness presents."

In high school, Garrett won elected offices in student government and
headed the lacrosse and cross country teams. A gifted student, he
wanted to study political science and biology at Hopkins.

At home, he cooked family dinners, helped his little sister with
homework, and surprised his mother with pancakes on her birthday.

"People likened him to the perfect child before he got sick," said his
mother, Kristan Kanyuch.

In 2007, the unusual behaviors started. He slept a lot. He emptied an
entire can of bug spray in his bedroom. When he came home for a
weekend from college, he pointed to a blister on his hand that had
formed from playing lacrosse.

"Look, I have gangrene," he said. "My hand is going to rot." Then he
tried to cut off his hand with a paring knife.

His family stopped him and took him to an emergency room for a psych
evaluation, but Garrett refused to wait and left.

A week later, Kanyuch got a call from the university. Her son was
failing every class. When confronted, Garrett looked at the F's and
calmly replied, "I'm not failing anything."

In the 1970s, Ayers-Moore saw the symptoms when her family picked her
brother up from Juilliard to head home to Cleveland, Ohio, for summer.

"The look in his eye was so different," she said. "It was like you
could see into his soul, he could look into yours. It sort of startled
me a little bit. I didn't know what to say to him. On the way from New
York, I pretended I was asleep. I didn't know what to say."

Paranoid schizophrenia

About three decades later, Nickole Kanyuch, 15, watched a similar
scenario unfold as her brother, Garrett, struggled with paranoid
schizophrenia and obsessive compulsive disorder.

"I watched the big brother who I had looked up to all my life fall
apart and become someone entirely new," she said. "The boy who was
destined for greatness, who worked long and hard for 12 years to lead
a successful life, was destroyed in a mere six months."

Garrett, who had once organized his 600 books by the Dewey Decimal
system, could hardly read two sentences. The voices in his head
drowned out the words on the page, he told his mother.

Garrett, who color coordinated the clothes inside his closet, could no
longer groom himself or shower. The voices told him the shampoo and
soap were poisoned.

Kristan Kanyuch quit her financial planning job to take care of him.
Despite taking medicine, Garrett's health fluctuated. One day he was
fine; the next, he threatened to kill the neighbors. Frustrated and
facing mounting debt, Kanyuch sought help.

She joined a mental health support group. At one session, she was told
to follow simple instructions from a counselor. Meanwhile, 10 people
who stood around her talked at once. While the chorus of voices
drowned out the instructions, she realized this was how her son lived
every day.

That night, Kanyuch hugged her son. "You have to be the most
courageous person. You wake up every day," she told him.

"That's when he explained to me the reason he sleeps," Kanyuch said.
"He doesn't hear the voices. He doesn't hear them telling him he's
fat, stupid, there's a conspiracy. It's a break for him to sleep."

Although no one knows where these voices originated, they could be
triggered by wiring problems in the brain, said McClellan, who
researches adolescent psychiatry. One theory is schizophrenia causes
difficulty distinguishing thoughts from their outside experiences, "so
they experience internal thoughts and perceptions as voices," he said.

Recovery

Garrett has been a subject in two research programs searching for
better schizophrenia treatments. His condition fluctuated, and, for
months, he was on suicide watch.

Schizophrenia is a difficult disorder to treat, because one medication
that soothes one patient can make another psychotic.

"Medication or dosages can't be matched absolutely with the
individual, so there is some of that trial and error," said Dr. Thomas
Bornemann, director of the Carter Center's Mental Health Program.

Garrett tried many drugs. Some made him drowsy, others volatile and
one drug made him gain 75 pounds. Severe side effects often cause
patients to stop taking medication.

For now, doctors seem to have found one that helps Garrett. Since
March, Garrett has been at a Maryland research center that looks into
the relationship between metabolism, tobacco and schizophrenia.

After a violent visit in August, Garrett, 21, had not been home until
Easter. During the recent visit, he played basketball, Yahtzee and Wii
bowling with his family.

"He was able to carry on a conversation and play card games," Kanyuch
said. "He was interacting."

At home, surrounded by reminders all his past achievements, Garrett
said: "Mom, I was on the top of the world. Now I'm in the gutter."

His mother disagreed: "Look at it as an opportunity."

"What?" he said.

"It's not an opportunity everyone would jump at," she told Garrett.
"But as you rehabilitate, as you grow an insight into your illness,
there may be things you deal with forever. But you've had significant
experiences that you may be able to use to help other people. There's
no place where insight and advocacy [for mental health] is needed more
than in politics, which is what you wanted to do."

A life with schizophrenia won't be easy, but some with the disorder
have graduated from college, earned doctorates and lead enriched
lives, she told Garrett.

"He doesn't understand the courage he has."

#122 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sat Jan 3, 2009 4:37 pm
Subject:: fabullous Pics of Earth taken by sunita williams
ashutos2
Offline Offline
Send Email Send Email
 
#121 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Thu Jan 1, 2009 5:35 am
Subject:: Hypnotherapy
ashutos2
Offline Offline
Send Email Send Email
 
Healing through hypnosis
2 Mar 2008, 0038 hrs IST, Sapna Sarfare
 Print   Email   Discuss  Share  Save  Comment Text:
Sheena (name changed) suffered from a host of personal and professional problems and was desperate for a solution. "I had relationship issues and
irritable spells," she says.

In the course of her search, she tried hypnotherapy. After a few sessions, Sheena says she felt she had a better handle on her situation. Life seemed a bigger, broader picture.

The relationship bothering her was no more, her health improved and she found she could cope better with situations. "I think it made me look at life more positively," she says.

Sheena, like others, is one of many turning to hypnotherapy as an alternative therapy.

Practitioners claim that many of us spend much of our time in a trance-like state anyway.

"Hypnotherapy is trying to activate your subconscious mind by switching your conscious mind off," says Bina Bakshi, a hypnotherapist.

"Normally, the conscious mind makes decisions and resists ideas. The first thing you need to know is that hypnosis is a very natural state. People go into hypnosis regularly without even realising it. If you were to listen to positive suggestions while in these naturally occurring trance states they would have an effect on you."

Clinical psychologist Shrimant Patil explains that psychologists use hypnosis to establish rapport with their patients and evolve a line of treatment. Says Dhansingh Chowdhury, a practising hypnotherapist, "If there is a problem, one should have sessions for the subconscious as the personality is locked in it. You have to put to sleep the conscious to reach the subconscious."

Almost 80% of problems in life are related to psychological problems, says Patil.

Techniques involve making the person comfortable, slowing down their breathing, making them stare at a spot and concentrate on feeling relaxed.

For Neha, hypnotherapy helped her deal with claustrophobia. "I had been through a number of surgeries and had become claustrophobic. After treatment, there has been a marked improvement, though I am not completely cured."

There's a growing curiosity about this form of therapy. "Almost 60 per cent of my patients come from outside Pune," says Bakshi. Hypnotherapy has proven effective in dealing with issues like adjustment problems, divorce, financial worries and obsessive compulsive disorders, she says.

There have always been misconceptions about hypnotherapy, however. Says Bakshi, "Hypnosis is often misunderstood. Many people believe it can force you to act and react in whatever way the hypnotherapist instructs. Hypnosis cannot make a person into someone different and cannot control a person's mind. It can only act upon what is within the person."

Sheena herself was hesitant about starting hypnotherapy. "Initially, I had fears. In reality, though, you are not unconscious, this is a common misconception. I never had much trouble with it. But it's still not an 'acceptable' thing to do. My family does not know about it."

Psychiatrist Susan Zachariah says hypnotherapy can be used clinically only on specific areas like in trauma cases where patients are unable to express emotions and suffer from severe anxiety. "This is where the usefulness of hypnotherapy comes in. It is useful in giving helpful suggestions under hypnosis. But the person must be willing to be induced. One cannot be hypnotised against one's wishes."

Also, to properly deal with the mind, one must not just be a trained psychologist but also know the patients and their psyche. Problems are deep-rooted and behaviours are complex".

Hypnotherapy also awaits the necessary acceptance by medical practitioners and universities. "It is legal only if you have a certificate in psychology. It only as a last resort that people turn to and are ready to try hypnosis. But I have found that medical professionals and psychologists are starting to accept this form of therapy," Bakshi states.

Recognition by the World Health Organisation in 1983 and India in 2003 has benefited hypnotherapy, with the Delhi University beginning a course in October 2007. Meghana Mahasabde, a clinical psycologist who underwent training as a hypnotherapist says, "Training in hypnotherapy is not easily available. It is present only as a guru-shisya tradition. You learn from experience. But there's not much risk factor as it is largely a talking treatment."

#120 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Fri Dec 26, 2008 4:49 pm
Subject:: merry christmas... 2008
ashutos2
Offline Offline
Send Email Send Email
 





Ashland College in Ohio does a beautiful Christmas card every year... this should get you into the Christmas Spirit...

Make sure you have your speakers on... and some patience...

 

http://ecard.ashland.edu/2004admission/index.html



--
A man is rich in proportion to the number of things he can afford to let alone.
~

.



#119 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Thu Dec 18, 2008 6:10 pm
Subject:: Fwd: WHY DOES RELIGION TURN VIOLENT?
ashutos2
Offline Offline
Send Email Send Email
 




WHY DOES RELIGION TURN VIOLENT?

A Psychoanalytic Exploration of Religious Terrorism

James W. Jones

This is a work in progress. It may look like a finished academic

paper with its text bristling with citations and references, but

that is an illusion—in Freud's sense. It is a wish—a wish to be

done with this terrible topic. Over the summer of 2001 a book

of mine was completed titled

Terror and Transformation: The Ambiguity

of Religion in Psychoanalytic Perspective

(Jones, 2002). Because

it had the word

Terror in the title and came out a few

months after 9/11, I have been swept up into a vortex of discussions

about religion and terrorism, a topic I find extremely foreign

to my experience and very aversive. Also, like many in the

New York metropolitan area, I find that 9/11 still casts a longer

shadow over my life (in ways that I still find hard to talk about)

than the World Trade Center towers ever cast when they stood

erect over lower Manhattan. As much as I want to escape from

these discussions, I have been unable to.

I am writing as a clinical psychologist of religion, interested

in the psychological dynamics involved in religion and especially

in religiously motivated violence and what that might contribute

to the psychology of religion. I am not proposing a general theory

of terrorism but rather asking what a psychological, primarily

psychodynamic, exploration of religious terrorism might tell

us about that phenomenon and about the psychology of religion

in general. Reading the literature on this topic I am struck by

the paucity of discussion of both of these factors—the psychodynamics

of religious terrorists and the religious aspect itself. In

part that is because most of the mainstream, scholarly literature

is written by social psychologists, not clinicians, and political scientists

rather than by scholars of religion or psychologists of reli-

Psychoanalytic Review, 93(2), April 2006

ÆÉ 2006 N.P.A.P.

168 JAMES W. JONES

gion. This paper is one small contribution to filling in that gap

in the discussion.

A factor that is virtually always cited by social psychologists

and political scientists writing about religiously driven terrorism

is the experience of shame and humiliation. For years, forensic

psychology has emphasized the connections between shame, humiliation,

and violence. Forensic psychologists cite numerous studies

correlating conditions of shame and humiliation with increases

in violence and crime, especially for males (Gilligan, 1996; Miller,

1993). For example, a psychiatrist working in prisons reports on

a study that suggests that every act of violence in the prison was

preceded by some humiliating event in the life of the prisoner

(Gilligan, 1996). Statistics show that in the United States, at least,

increases in crime follow exactly increases in the number of unemployed

men. Feelings of humiliation on the part of Arab populations

have been one of the most frequently cited "root

causes" of the turn to fundamentalist Islam (Abi-Hashem, 2004;

Davis, 2003; Hassan, 2001). One Palestinian trainer of the bombers

has said, "Much of the work is already done by the suffering

these people have been subject to. . . . Only 10 percent comes

from me. The suffering and living in exile away from their land

has given the person 90 percent of what he needs to become a

martyr" (Davis, 2003, p. 154). A Palestinian psychiatrist reports

that "humiliation is an important factor motivating young suicide

bombers" (quoted in Victoroff, 2005, p. 29). By one estimate,

over 90 percent of the recruits to militant Palestinian

groups come from the villages and camps suffering the most

from the Israeli presence, where the humiliation is greatest and

the struggle is most intense (Post, Sprinzak, & Denny, 2003, p.

173). Hassan reports: "Over and over I heard them [militants]

say, 'The Israelis humiliate us. They occupy our land, and deny

our history'" (p. 38). Like many New Religious movements, the

Japanese cult Aum Shinrikyo—some of whose members released

sarin nerve gas in a Tokyo subway and also murdered several

people—regularly engaged in rituals of shaming and humiliation

of its members. Members were often harangued by the guru,

kept in isolation, or made to wait hours for their leader to appear

while chanting over and over, "Master, please appear" (Lif-

WHY DOES RELIGION TURN VIOLENT? 169

ton, 2000; other, even more horrific acts of humiliation are described

in Reader, 2000, pp. 137–141).

While often rooted in social and political circumstances,

shame and humiliation are profoundly psychological, and often

spiritual, conditions. By holding out an absolute and perfect

ideal—whether it is a divine being or a perfect guru or master or

sacred text—against which all mortals inevitably fall short and by

insisting on the "infinite qualitative difference" (in the words of

Soren Kierkegaard) between human beings and the ideal, religions

can easily exacerbate and play upon any natural human

tendency toward feelings of shame and humiliation (McNish,

2004; Pattison, 2000). I would suggest the more a religion exalts

its ideal, or portrays the divine as an overpowering presence and

emphasizes the gulf between finite human beings and that ideal

so that we must feel like "worms, not human" (in the words of

the Psalms), the more it contributes to and reinforces experiences

of shame and humiliation.

In addition, many writers have noted the connection between

feelings of shame and disgust with the body and embodiment.

As many authors have commented, a classic example in

the West is St. Augustine, who virtually single-handedly made

the doctrine of original sin central to the Western Christian understanding

of human nature. It is not coincidence that this proponent

of the idea that we are born sinful and impure continually

(in his book the

Confessions) expresses revulsion at anything

associated with his body. But such a theological linkage of the

body with feelings of shame is (unfortunately) not unique to Augustine

but can be found in the traditional texts of many religions.

One of the Muslim leaders of the 9/11 attacks wrote some

years earlier in his will that no woman or other unclean person

should touch his body and that his genitalia be washed with

gloved hands. Even the very secular, science-fiction-based "Heaven's

Gate" cult in the United States—most of whose members

committed ritual suicide in 1997—recommended castration for

all the men involved.

If it is the case, as much research suggests, that there is a

linkage of shame, humiliation, and violence, one way that religion

can contribute to terrorism is by creating and/or reinforcing

and potentiating feelings of shame and humiliation, which

170 JAMES W. JONES

in turn increase the likelihood of violent outbursts. And this increased

potential for violence needs to be channeled in socially

approved ways. By fomenting crusades, dehumanizing outsiders,

and encouraging prejudices, fanatical religions provide ready, religiously

sanctioned, targets for any increase in aggression. While

much of the humiliation that fuels certain acts of terrorism

might begin in social and cultural conditions, fanatical religions

may build upon that and establish a cycle wherein their teachings

and practices increase feelings of shame and humiliation,

which intensify aggressive feelings, as well as then providing targets

for that aggression.

One common belief, which many commentators mention,

of fanatically violent religious movements is their apocalyptic vision

of a cosmic struggle of the forces of the all-good against

the forces of the all-evil (Juergensmeyer, 2000; Kimball, 2002;

Wessinger, 2000). Virtually all religious terrorists agree that they

are locked in an apocalyptic battle with demonic forces, usually,

that is, with the forces of secularism. The late Rabbi Meir Kahane,

whose Jewish Defense League was responsible for numerous attacks

on Muslims in the United States and Israel, said bluntly,

"Secular government is the enemy" (Juergensmeyer, 2000, p. 55).

Kahane's arch enemy, the founder of Hamas, Sheik Ahmed n

Yassin, told a reporter, "There's a war going on" not just against

Israeli occupation but against all secular governments including

the Palestinian authority because there "is no such thing as a

secular state in Islam" (Juergensmeyer, 2000, p. 76). Asahara, the

founder of the Aum Shinrikyo cult is reported to have shouted

again and again at his followers, "Don't you realize that this is

war" (Lifton, 2000, p. 56) and to have insisted that his group

existed "on a war footing" (Lifton, 2000, p. 60). The Reverend

Peter Hill, who shot and killed a physician in front of a family

planning clinic in the United States, justified his actions to an

interviewer as being part of a "great crusade conducted by the

Christian subculture in America that considers itself at war with

the larger society, and to some extent victimized by it" (Juergensmeyer,

2000, p. 36). Juergensmeyer (2000) concludes his investigation

of religiously sponsored terrorism around the globe,

Terror

in the Mind of God

, with the comment that "what is strikingly

similar about the cultures of which they [religious terrorists] are

WHY DOES RELIGION TURN VIOLENT? 171

a part is their view of the contemporary world at war" (p. 151).

Klein, Fairbairn, and others have written about the obvious psychoanalytic

antecedents to this splitting of the world into all-bad,

all-good camps.

Violently apocalyptic movements not only split the world

into irreconcilable opposites of good and evil, they also look forward

to the climatic end of history, when evil will be violently

eradicated. Apocalyptic religion is not only about dividing the

world, it is also about purifying the world. In the apocalyptic

mind-set, purification is almost always bloody. Rather than envisioning

a spiritual process through which the unholy is transformed

into something holy, apocalyptic religions are full of fantasies

and images of violence, warfare, and bloodshed in which

the unholy is destroyed in the most gruesome fashion imaginable.

Here purification becomes linked with violent death. We

must explore the psychological dynamics involved in this linkage

of purification and violent death.

The underlying theme of death and rebirth is common in

virtually all the world's religions. Virtually all the traditions say

that some process of dying—to self-centeredness, to a false self,

to antispiritual cravings—is central to spiritual transformation.

Apocalyptic religion takes this theme and historicizes it. Death

and rebirth are now something that can and must happen within

history, in real time. Another theme that runs through this material

is the increasing spiritual and moral decline of the world,

which is often pictured as sinking rapidly into moral and spiritual

oblivion, a world heading for disaster. One Aum Shinrikyo

member reports feeling that "the world was getting worse, pushing

itself towards Armageddon with its increasing evil" (Lifton,

2000, p. 93). Rottenness of the world is just crying out for purification

to set things right. Things are getting so bad that only a

drastic intervention can turn things around. Lifton (2000) describes

Aum Shinrikyo, in a phrase that could equally well be applied to

many religiously motivated terrorist groups, when he writes that

they were driven by "the relentless impulse toward world-rejecting

purification" (p. 204).

We should note that, while Aum Shinrikyo is often mentioned

in books on religiously motivated terrorism because of its

roots in the syncretistic Japanese religious milieu, Lifton's ac-

172 JAMES W. JONES

count makes clear that the cult relies as much on science, science

fiction, and the idealization of high technology as on religion

(see also Reader, 2000, pp. 185–187). In that sense Lifton links

it with the "Heaven's Gate" UFO cult. Both groups would have

been impossible apart from a milieu saturated by popular science,

science fiction, video game culture (with its merger of science

and violence), and the idealization of technology. Yet in

popular accounts of Aum Shinrikyo, religion is featured and science

and technology ignored. But the themes of apocalyptic violence

and rebirth through death are hardly absent from popular

science-fiction culture, both in the United States and Japan.

Apocalyptically historicized or not, the theme of purification,

often linked to themes of death and rebirth, appears central

in virtually every major religious tradition. Some, like Durkheim

(1965), have argued that the split between the pure and

the impure, the sacred and the profane, is the defining characteristic

of the religious consciousness. Certainly this seems especially

true of fanatical religions at war with the impure and unrighteous

world around them. The traditional sectarian response has

been to withdraw from the sinful world and create islands of

purity separate from it (for example, the Amish people). Religious

terrorists are not content to simply withdraw and protect

their purity; they seek to actively transform and purify the surrounding

world. Asahara is described as developing a "vision of

an apocalyptic event or series of events that would destroy the

world in the service of renewal" (Lifton, 2000, p. 203).

In many religions the theme of purification is linked with

the theme of sacrifice. The Latin root "sacri-ficium" means to

"make holy." Sacrifice is a way of making something holy, of

purifying it. Sacrifices are offerings to the divine and to the community.

But they are a special kind of offering in that what is

given is destroyed. But something is not only destroyed, it (or

something related to it, like the religious community) is also

transformed. Something is offered; something is made holy.

The practice of sacrifice may go back to the very foundations

of religion. The early Vedas in India center around various

sacrificial rituals, and much of the Hebrew Torah is taken up

with instructions for conducting sacrifices. Of course, Hinduism

later gave rise to the Upanishads with their elaborate metaphysi-

WHY DOES RELIGION TURN VIOLENT? 173

cal discussions as well as to a wide range of yogic, meditational,

and devotional practices. Furthermore, the Hebrew prophets

and later writings came to ridicule the idea that God requires

bloody sacrifices, insisting instead on a "broken and contrite

heart" (Isaiah) and "justice, mercy, and humility" (Micah). But

the theme of sacrifice did not die out entirely. It was taken up

by some strands of Christianity that continued to insist, with the

author of the Letter to the Hebrews (apparently a conservative

first-century Jewish convert to Christianity), that "without the

shedding of blood, there is no forgiveness of sins." One of the

burdens of this paper will be to attempt to unpack the psychology

behind this connection between purification or redemption

and the shedding of blood, since that theme appears so central

to so much religiously motivated violence.

The theme of sacrifice often appears central in the larger

religious context from which "human bombers" emerge.

1 For example,

the leader of the 9/11 attacks called on his comrades to

"purify your soul from all blemishes" and spoke to them of "offering

sacrifices and obedience" in "these last hours" (Atta, n.d.,

Last Letter

, discussed later in this paper). There he also refers to

those whom they will kill as animals being ritually sacrificed. It

underscores the sacrificial, that is to say, religious, nature of

these actions. The terrorist is sacrificing both himself and his

victim.

In reference to this theme of sanctification by self-sacrifice,

Strenski (2003) writes that "The 'human bombers' are regarded

as 'sacred' by their communities of reference. They have been

'made holy' in the eyes of the community that 'accepts' them

and their deed. They are elevated to lofty moral, and indeed,

religious levels, as sacrificial

victims themselves or as kinds of

holy saints" (p. 8). For example, Hassan (2001) reports that in

Palestinian neighborhoods:

Calendars are illustrated with the "martyr of the month." Paintings

glorify the dead bombers in Paradise, triumphant beneath a

flock of green birds. The symbol is based on a saying of the

prophet Mohammad that the soul of a martyr is carried to Allah

in the bosom of the green birds of paradise. . . . A biography of a

martyr . . . tells of how his soul was borne upward on a fragment

of a bomb. . . . [An imam] explained that the first drop of blood

174 JAMES W. JONES

shed by a martyr during jihad washes away his sins instantaneously.

On the Day of Judgment, he will face no reckoning. On the

Day of Resurrection, he can intercede for several of his nearest

and dearest to enter Heaven. . . ." (p. 39)

Scholars familiar with the hagiographic traditions of the world's

religions will see many common themes here—for example, the

images of Christian saints and Buddhist Bodhisattvas borne up

to paradise and ensconced in the highest heavens where, purified

and sinless, they can intercede for others. By their offering

and sacrifice, the human bombers and other martyrs have indeed

become holy. Along this line, a Palestinian militant said, "It

is attacks when a member gives his life that earn the most respect

and elevate the bombers to the highest possible level of

martyrdom" (Post et al., 2003, p. 179). Likewise, the Tamil Tigers

describe call their suicide bombings in Sri Lanka by a world that

means "to give oneself." Their actions are "a gift of the self." In

joining the Tigers one takes an oath in which "the only promise

is I am prepared to give everything I have, including my life. It

is an oath to the nation" (Strenski, 2003, p. 22). A Palestinian

questioned by Post and his colleagues angrily rejected their appellation

of suicide and told them, "This is not suicide. Suicide

is selfish, it is weak, it is mentally disturbed. This is

istishad (martyrdom

or self-sacrifice in the service of Allah)" (Post et al., 2003,

p. 179). It must be noted that this understanding of martyrdom

and self-sacrifice is not traditional in Islam, and it has been condemned

by many leading Muslim clerics and scholars around the

world (for references see Strenski, 2003; Davis, 2003). Rather, it

represents a major theological innovation on the part of the radical

Islamicists like bin Laden.

That "martyrdom operations" are understood by their participants

as religious acts is made clear by the rituals that surround

them. Mohammed Atta, the leader of the 9/11 terrorists,

left for posterity a letter, the major themes of which are obedience,

prayer, union with God, and sacrifice. Atta calls on his

comrades to engage in devotions as preparation for their mission:

Remember the words of Almighty God. . . . Remind yourself of

the supplications. . . . Bless your body with some verses from the

Qur'an. . . . . Pray the morning prayer in a group and ponder the

great rewards of that prayer. Make supplications afterward, and

WHY DOES RELIGION TURN VIOLENT? 175

do not leave your apartment unless you have performed ablution

before leaving. . . . Read the words of God. (Atta, n.d.,

Last Letter)

Such religious ritualizing was not unique to the 9/11 cell; it is a

normal and crucial part of the human bomber's mission:

Just before the bomber sets out on his final journey, he performs

a ritual ablution, puts on clean clothes, and tries to attend at least

one communal prayer at a mosque. He says the traditional Islamic

prayer that is customary before battle, and asks Allah to forgive

his sins and bless his mission. He puts a Koran in his left breast

pocket, above the heart, and he straps the explosives around his

waist or picks up briefcase or a bag containing the bomb. The

planner bids him farewell with the words, "May Allah be with you,

may Allah give you success so that you achieve Paradise." The

would-be martyr responds, "

Inshallah, we will meet in Paradise."

Hours later, as he presses the detonator, he says, "Allahu akbar"—

"Allah is great. All praise to Him." (Hassan, 2001, p. 41)

Atta's letter goes on to stress the need for continual supplication

throughout the 9/11 hijacking and the assurance of divine protection,

favor, and reward: "Everywhere you go, say that prayer

and smile and be calm, for God is with the believers. And the

angels will protect you without you feeling anything," Atta writes

to his comrades. There are few references in his letter to anger

or revenge: rather, the driving motivation is reunion with God.

The letter makes it clear that the terrorists were not seeking political

or social goals but rather that they "are heading toward

eternal paradise." A leader of Hamas said "Love of martyrdom

is something deep inside the heart. But these rewards are not in

themselves the goal of the martyr. The only aim is to win Allah's

satisfaction. That can be done in the simplest and speediest manner

by dying in the cause of Allah" (Hassan, 2001, p. 36).

The same attitude emerges from an interview with a Palestinian

suicide bomber who survived a failed attempt and a gun

battle with Israeli troops. Like Atta he describes his preparation

for his "martyrdom operation" as a spiritual discipline.

We were in a constant state of worship. We told each other that

if the Israelis only knew how joyful we were they would whip us

to death. Those were the happiest days of my life. . . . We were

floating, swimming, in the feeling that we were about to enter

eternity. We had no doubts. We had made on oath on the Koran,

176 JAMES W. JONES

in the presence of Allah. . . . I know there are other ways to do

jihad. But this one is sweet—the sweetest. All martyrdom operations,

if done for Allah's sake, hurt less than a gnat's bite. (Hassan,

2001, pp. 36–37)

On a similar note, the killer of a doctor outside a family planning

clinic in the United States says he was comforted by reading

the Psalms on his way to commit the murder. One of the perpetrators

of the 1993 bombing of the World Trade Center is reported

to have told a journalist that secular Americans will never

understand why he did what he did because they miss "the soul.

. . . The soul of religion, that is what is missing" (Juergensmeyer,

2000, p. 69).

Hence, the 9/11 attacks were not a political act; they were

a religious act. Therefore, the psychology involved here is that

of religion. Although humiliation and relative deprivation clearly

play a part in much of the terrorism in the Middle East, the

unusual sociological variables—poverty, lack of education, and

the like—often appear to play little role and provide little predictive

value. One of the best predictors is religiosity. The Singapore

Parliamentary report on captured members of terrorist cells in

Southeast Asia emphasizes this connection: "These men were not

ignorant, destitute, or disenfranchised. All 31 men had received

secular education. . . . they held normal, respectable jobs. . . . As a

group, most of the detainees regarded religion as their most important

personal value" (quoted in Atran, 2003, p. 1537).

One of the most extreme examples of the linkage of death

and purification is Asahara's doctrine of killing a person in order

to save them (called

poa), which became increasingly important

as Aum felt more threatened by surrounding society. Such

a doctrine, based on Asahara's reading of esoteric Tibetan Buddhism,

clearly provides the kind of sanctification of killing found

in every case of religiously sponsored terrorism. In addition, this

doctrine supports an inability to empathize with victims, thereby

easily promoting what the social psychologist Waller (2002) calls

their "social death." Many of Aum's remaining members do indeed

express an astonishing lack of empathy for the victims of

their group's actions. The most extreme is the Aum member

who responded to Reader's (2000) mention of the subway attack

with "Wonderful, wasn't it?"—because of the attention it brought

WHY DOES RELIGION TURN VIOLENT? 177

to Aum (p. 222; see Maekawa, 2001, for many more examples of

this lack of empathy for the victims).

Shimazono (2001), to some extent, and Watanabe (1998,

2005), more strongly, lay much of the blame for Aum's crimes

on Asahara's doctrine of

poa. This would be another example of

the idea of sacrifice (either of oneself or others) leading to one's

sanctification that is central in much religiously sponsored terrorism.

But in the case of Aum, psychologically we need to ask,

why does such an extreme doctrine as

poa take root in some

people's minds? Is it primarily, as Shimazono and Lifton seem

to imply, because of their extreme devotion to guru Asahara? Or

is there a deeper, psychological reason that inclines people to

accept the idea of sanctifying oneself (and the other, too, in the

case of

poa) through death?

Once again we are back to the psychodynamic linking of

holiness and purification with death that also is found in many

examples of religiously sponsored violence. The theme of purification

was central in Asahara's message virtually from the beginning;

his techniques were supposed to enable individuals to rid

themselves of "bad karma" and other impurities. Themes of purity

and purification are central in Japanese Shinto, and thus

were surely present in Asahara's consciousness and that of his

disciples. But such themes are present in some form in virtually

every religion. They not in the least unique to Shinto, Aum, or

violent religious groups. Again, psychologically it is not the

themes of sanctification or purification that are at issue. Rather,

it is their linkage with violence and death that matters in the

psychology of religiously motivated terrorism. This theme of sacrificing

one's self and one's victim in order to sanctify or purify

both becomes more and more prominent in Asahara's religious

rhetoric as Aum Shinrikyo turns more violent and Asahara seeks

to justify the group's murderous actions (Shimazono, 2001;

Watanabe, 1998, 2005).

Since the human bombers and the members of Aum Shinrikyo

are offering a religious sacrifice, Strenski (2003) argues,

their actions are not primarily motivated by "a utilitarian or

pragmatic calculus" (p. 26). One important and perhaps unhappy

practical conclusion of this situation is that it is mistake

to seek to understand religiously motivated terrorists using the

178 JAMES W. JONES

game theoretic or rational choice models so prominent in the

social sciences these days (for relevant reviews, see Victoroff,

2005, as well as Moghaddam & Marsella, 2004). Counterterrorism

policies based on either appealing to the religiously motivated

terrorists' self-interest or frightening them into surrendering

by an overwhelming show of force will probably have little

success. The religious drive to sacrifice and make holy one's life

and one's cause transcends and subsumes any pragmatic or

purely self-interested motivations. Knowing themselves to be engaged

in religious acts of sacrifice and understanding the West's

orientation away from the spiritual and toward the pragmatic is

one of the reasons why militant Islamicists insist over and over

that the West will never understand them.

2

Virtually every report on militant Muslims stresses the reward

of entering paradise as a major motivator for their actions

(Davis, 2003; Post et al., 2003; Hassan, 2001). In Western accounts,

often this is accompanied by descriptions of scores of

beautiful virgins waiting to welcome the adolescent male martyr

home, even though most traditional Islamic scholars insist that

the delights of paradise are not erotic. But clearly the desire to

be with God is a powerful motivation at work here.

A Palestinian militant, when asked about his motivation, replies,

"The power of the spirit pulls us upward," (Hassan, 2001,

p. 37). Atta tells his fellow hijackers: "You should feel complete

tranquility, because the time between you and your marriage (in

heaven) is very short. Afterward begins the happy life, where

God is satisfied with you and eternal bliss" (Atta, n.d.,

Last Letter).

A Palestinian recruiter said of his methods of recruitment,

"We focus his attention on Paradise, on being in the presence

of Allah, on meeting the Prophet Muhammad, on interceding

for his loved ones so that they too can be saved from the agonies

of Hell" (Hassan, 2001, p. 40). A Palestinian arrested by the Palestinian

Authority before he could carry out his mission said of

Paradise, "It is very, very near—right in front of our eyes. It lies

beneath the thumb. On the other side of the detonator" (Hassan,

2001, p. 40).

Clearly this is not unique to fanatical religious. Quite the

reverse. The desire for an experience of union with a transcendental

or divine reality appears as fundamental in virtually every

WHY DOES RELIGION TURN VIOLENT? 179

religion, whether it is the universal, nameless primal Source of

the Upanishads, Neo-Platonic Christian mysticism, and much

Mahayana Buddhism, or the personally beloved Other of devotional

Hinduism, pietistic Christianity, or Tibetan guru yoga, or

the divine Creator of traditional Judaism and Islam. This desire

for spiritual reunion may well be the beating heart of every living

religion.

What is unique to fanatical religions is the linkage of the

desire for spiritual reunion with violence, especially the violence

of sacrificial killing or apocalyptic purification. It may be this

linkage of a well-nigh universal and powerful spiritual desire

with the themes of bloody sacrifice and purification through violence

that turns spiritual longing into terrorist action.

Psychologically speaking, why is the shedding of blood experienced

as necessary for redemption?

Clearly it seems connected to the image of God that is at

work here—the image of a vengeful, punitive, and overpowering

patriarchal divine being. The believer must find a way to relate

to an omnipotent being who appears to will the believer's destruction.

The believer must humiliate and abject himself, feeling

himself profoundly worthless and deeply guilty. Furthermore,

the punitive, omnipotent being must be appeased, placated. A

bloody sacrifice must be offered. So we return again to the combination

of a wrathful, punitive image of God, the insistence on

purification at any cost, and the theme of bloody sacrifice.

3

The God that demands sacrifice as the means of purification

is an angry, punitive God. Here the psychologist of religion

can contribute to the discussion by pointing to some of the correlates

of such an image of God. There is research that suggests,

at least for religiously committed populations, that punitive and

wrathful images of God are associated with external locus of control,

anxiety and depression, and less mature object relations

(Brokaw & Edwards, 1994; Spear, 1994) The reverse has also

been found to be true, that a more benevolent internal representation

of God is associated with more mature psychological development

and the capacity for more mature object relations. A

believer's capacity for object relations encompasses his or her

religious expressions (Jones, 1991). Thus it makes theoretical as

well as empirical sense that a person who envisions God as

180 JAMES W. JONES

wrathful or punitive would also be inclined toward more rigid

splitting and have less capacity for empathy—traits that appear

to characterize many religiously motivated terrorists.

So sacrifice and redemption, bloodshed and spiritual transformation

become linked when the deity to be appeased by sacrifice

is humiliating and punitive. But there was no transcendental

deity in Aum. As Watanabe (n.d.) astutely points out, when Asahara

had his vision anointing him with a messianic vocation, the

result was not a religion of devotion to that god—as is usually

the result in the history of religions—but rather a cult based on

devotion to Asahara himself. So did Asahara himself serve as a

humiliating but sacred Other that had to be appeased by abject

submission and by sacrificing oneself and others? We can surmise

so, but we do not really know. We can suggest that whatever

is the psychological connection between purification and

the shedding of blood, which seems operative in so much religiously

motivated violence, it was probably present in at least

some Aum members as well.

From a clinical standpoint, what appears most salient in the

turn toward violence on the part of religion are the themes of

shame and humiliation, the apocalyptic splitting of the world

into all-good/all-evil camps, the wrathful, judgmental image of

God, the drive for purification, and the authoritarian concern

with submission and prejudice against outsiders (Altemeyer &

Hunsberger, 1992). Research suggests that shame and humiliation

may be crucial elements in most religiously sponsored violence.

Religion can become involved with humiliation-driven

violence in one or both of two ways. One, people may be humiliated

by the circumstances of their lives (Palestinians under Israeli

occupation, Chechens under Russian occupation, Iraqis under

American occupation), and their religion may play upon that

humiliation, potentiating it and channeling it for its own purposes.

We should note that religion may also mute and transform

that humiliation rather than reinforce it, as the Dali Lama

is trying to do with the Tibetans under Chinese occupation and

as Martin Luther King attempted to do with the humiliation of

African-Americans in the face of American racism.

Second, religions may directly evoke and exacerbate feelings

of shame and humiliation. Images of a wrathful punitive

WHY DOES RELIGION TURN VIOLENT? 181

deity, a revered master or leader who harangues and humiliates

his disciples, or a sacred text read in a way to aggravate shame

and condemnation are all ways that religions can intensify those

feelings. Here we can begin to see some of the connections

among these themes often found together in religiously motivated

terrorists, that is, their punitive image of God or some

other religious object and their humiliation-driven turn toward

violence. My suggestion is that when the divine, the revered master,

or the sacred text is experienced as a source of humiliation

and shame, the possibility of violence increases. Previously I argued

(Jones, 2002) that idealization was central to religion and

to religious violence (and also to religious transformation, hence

the subtitle of my book

The Ambiguity of Religion). Here I am

revising that thesis to say that it is not idealization alone that is

central to the psychology of religious violence but an idealized

object that is also a source of shame and humiliation. The psychodynamic

connection to something sacred that results in religious

violence is not just a tie to an idealized object but, in addition,

to an idealized humiliating or overpowering object. Perhaps

that is why Buddhist and Hindu religions, whose devotees also

have ties to idealized objects—pantheons of divine beings or enlightened

masters—less often produce violent actions. These objects,

while idealized, are rarely humiliating and persecutory.

When they do turn punitive and humiliating (as perhaps in the

case Aum Shinrikyo or the devotees of Kali), then these groups

do turn violent.

4 In addition, research done with religious believers

in North America suggests that such punitive images of God

tend to be associated with an external locus of control, a lack of

empathy for others, a tendency toward psychological splitting

and less self-esteem. Again, there may be connections between

the punitive experience of the divine, authoritarian personality

traits, and the appeal of an apocalyptic polarization of the world.

In addition, the self-aggrandizement that Juergensmeyer (2000)

argues comes with being a part of the army of the righteous may

have a special appeal to those whose self-esteem needs bolstering.

The drive for reunion with, by submission to, this humiliating

but idealized object sublates all other human desires. The

desire for God overwhelms all connections between human beings.

The result is a detachment from empathic connections be-

182 JAMES W. JONES

tween human beings and their replacement by a totalizing connection

with God alone. By identifying with God and what is

supposed to be God's perspective, other human beings appear

small and insignificant. As opposed to those religions that see

each human spirit as infinitely precious, created in God's image,

terrorist forms of the religious imagination envision individual

human beings as insignificant in the larger context of God's eternal

plan. This is a religion focused on obedience, submission,

purification, and earning divine favor. One might call these the

central themes of a patriarchal religion. Although there are

women martyrs in Palestine and Chechnya, the 9/11 action was

an all-male rite. Indeed, most of the fanatical religious groups

are clearly male dominated (Lawrence, 1989). So part of the psychology

involved is the psychology of patriarchal religion.

Freud himself provides one of the most profound analyses

of patriarchal religion in his book

Totem and Taboo (a fuller discussion

of

Totem and Taboo can be found in Jones, 1996). Here,

instinct-driven ambivalence is the key to understanding the genesis

of religion and culture. At first the sons of the primal horde

hated their father, who stood in the way of their boundless desire.

But they loved and admired him too. After murdering him,

their affection for him, which they had had to deny in order kill

him, reappeared as guilt and remorse. This is how guilt, on

which all religion depends, originated (Freud, 1913, p. 143).

The murderous sons of the primal father, the harbingers

of culture and religion, had to make peace with their returning

repressed guilt. A substitute father had to be found. Like Freud's

phobic child-patient little Hans—who projected his fear of his

father onto an animal—the guilty sons projected their feelings

onto an animal, and totemism, and with it religion, was born.

Totemism is the beginning of religion; patriarchal theism is the

end. Freud (1913) remains convinced that the root of every religion

is a "longing for the father" (p. 148). The first religious

object, the totem, could only be a surrogate father. As time went

on and the primal murder faded into unconsciousness, an object

entered consciousness that carried a more complete resemblance

to the lost father—a god "in which the father has regained his

human shape" (p. 148).

The oedipal legacy of patriarchal religion becomes the lens

WHY DOES RELIGION TURN VIOLENT? 183

through which Freud (1913) sees all religious history. "The god

of each of them is formed in the likeness of the father, his personal

relation to God depends on his relation to his father. . . .

at bottom God is nothing other than an exalted father" (p. 47).

Freud, convinced that the murder of the father and its continual

replay in fantasy and culture is the hinge on which history turns,

can easily read religious development forward or backward from

that point.

The original theory of the process of internalization in

Mourning

and Melancholia

implies that the boy should internalize an

image of his mother, because she is the lost object. But in the

third chapter of

The Ego and the Id, Freud complicates the earlier

theory (for example, by invoking the category of bisexuality) in

order to argue that in dissolving the Oedipus complex the males

of the species, the creators of culture, simultaneously renounce

their attachment to their mother and internalize an image of

their father. For it is the internalized image of the father, as egoideal,

that is the foundation of culture and religion. In the resolution

of the male Oedipus complex the connection to the

mother is displaced by an identification with the father.

The same displacement of the feminine influence by the

masculine takes place in psychoanalytic theorizing, as the preoedipal,

mother-dominated period is downplayed in favor of the

developmental centrality of the oedipal, father-dominated stage.

Keeping to the parallel between individual and cultural development,

Freud (1913) confesses he can find no place "for the great

mother goddesses, who may perhaps in general have preceded

the father gods" (p. 49). This oversight surely parallels the fact

that he can find no place in his theory for the preoedipal, maternal

period in human development except its displacement by

a normative patriarchy. With the coming of the oedipal period

individually and prehistorically, the normative ethos of patriarchy

returned. "With the introduction of father deities a fatherless

society gradually changed into one organized on a patriarchal

basis. The family was a restoration of the former primal horde

and it gave back to fathers a large portion of their former rights"

(Freud, 1913, p. 149).

In a letter to Freud, responding to

The Future of an Illusion,

Freud's friend Romain Rolland, a student of Hindu religion and

184 JAMES W. JONES

biographer of Ramakrishna and Vivekenanda, proposed a preoedipal

origin to religion in a "feeling of something limitless, unbounded-

as it were, oceanic . . . a purely subjective fact, not an

article of faith." Freud, having firmly committed himself to the

centrality of the father, the father God, the oedipal struggle, and

the masculine gender, must deny Rolland's claim that religion

arises from preoedipal, maternal dynamics. The only definition

of religion Freud will consider is a patriarchal religion of law

and guilt built around the father God.

Freud's analysis of religion depends on a specific image of

God. The patriarchal God of law and conscience is the only religion

Freud will countenance. If he were to give up that paternal

representation of God as normative, his argument would lose

much of its force. Freud reproduces the exclusive, patriarchal

monotheism of Western religion in his theory of the exclusively

oedipal and paternal origins of culture, religion, and morality.

Freud must insist that religion is essentially patriarchal, for that

is the only religion that fits within the frame of the oedipal

drama and that can easily be derived from the instinct theory.

In tying morality tightly to the Oedipus complex so that "religion,

morals, society converge in the Oedipus complex," Freud

(1913, p. 157) is insisting that morality consists mainly of rules

and prohibitions. Freud's tendency to limit morality to a set of

prohibitions, like his restriction of religion to patriarchal theism,

follows naturally from the centrality of the oedipal period in his

theory. Again, the importance of the preoedipal, maternal period

has been forgotten. Just as forms of religion may be rooted

in preoedipal, maternal dynamics, so likewise with morality.

Along with a postoedipal, paternal morality of law and authority,

there may well be a preoedipal, maternal morality of connection

and relationship. An appreciation of the integrity and centrality

of preoedipal dynamics might point to an ethic of relatedness in

which the maintenance of connections between people is more

central than the imposition of rules. Such an ethic has been

taken up by many feminist writers. Such a relational, feminist

approach to moral reasoning parallels the relational view of human

nature found in contemporary psychoanalysis.

Freud's analysis points to the deep psychodynamic connections

between patriarchal cultures, paternalistic deities, and guilt-

WHY DOES RELIGION TURN VIOLENT? 185

engendering religions. Such connections, common in the history

of religion, are not accidental, but can be explained by the Oedipus

complex understood not as biological necessity but as cultural

expression. Exploring oedipal dynamics reveals the ways

males in a patriarchal culture identify with the father and internalize

the motifs of dominance and submission, detached impersonal

experiences of power, and the need for distance. When

what is sacred is encountered in the context of these masculine

identifications, religion is experienced in terms of dominance

and submission and transcendental power and control. Furthermore,

when morality is worked out in this context, the result

again is an ethics of moral principles and law backed up by sacred

power and dominance. This develops a patriarchal religion

of divine law and power in which submission to the law of the

father is the primary moral imperative and guilt the main religious

emotion.

Along with the dynamics of patriarchy, another psychodynamic

element in much religiously motivated terrorism is this

Manichean splitting of reality into all-good and all-evil, pure and

impure, categories and groups. Fairbairn (1952) describes a clinical

constellation that appears to map readily onto certain religiously

motivated terrorist groups. In order to maintain the experience

of the parents as "good," the inevitably dependent

child splits any experience of badness off from the parents and

takes it on himself. The child maintains an idealized view of the

parents at his own expense, experiencing himself as bad and

seeing the parents, on whose goodness he depends, as good. The

child sanitizes the image of the parents at the cost of his own

self-esteem and self-worth, protecting his idealization of them by

taking the pain and pathology of their relationship into himself,

bearing "the burden of badness" (p. 65). Thus a dichotomy is

created in the child's, and later the adult's, experience between

an all-good, overly idealized, external parental object and an entirely

bad self.

The person may then turn the experience of being bad

against himself. Here religion may play a crucially facilitative

role. In that psychological context, encountering an overly idealized

other (perhaps God, or a religious teacher, text, or institution

that claims divinity and perfection) inevitably invokes a split-

186 JAMES W. JONES

ting of experience into all-good and all-bad domains. Idealizing

the other means inevitably denigrating oneself and everything

connected to oneself. This splitting is common in those religious

communities that call upon their devotees to denigrate and demean

themselves and bemoan their unworthiness in the face of

some ideal other. It is not accidental that Fairbairn (1952) uses

theological language to describe this clinical syndrome and the

splitting that results from it, calling it "the moral defense against

bad object" and saying "it is better to be a sinner in a world

ruled by God than to live in a world ruled by the Devil" (p. 67).

Another possibility, besides turning the burden of badness

against oneself, is to expel the feeling of badness from oneself

by projecting it onto the outside world. Here again, religion may

facilitate such a move. Weighed down by this sense of badness,

a person may identify with an idealized tradition or group and

then project the sense of badness onto some outside person or

group, thereby seeing some other group, race, or religion as evil.

The experience of badness that the individual has taken into

himself is so painful that often it must be discharged by being

projected onto a despised group. Religious groups that encourage

this splitting of the world into all-good and all-bad camps

often find others to demonize and carry this sense of badness.

Research on religious fanaticism and terrorism provides countless

examples of this dynamic. It is not coincidence that this research

has found the more fanatical groups are also the most

racist, homophobic, and anti-Semitic (Altemeyer & Hunsberger,

1992). Thus the psychological appeal of what Juergensmeyer

(2000) calls satanization. Such a denigration of the other, an almost

inevitable result of the moral defense with its overidealization

of an object and the splitting of the world, makes the denigrated

other a ready victim of terrorist violence.

In the face of an uncritical overidealized object, religious

devotees experience shame and a sense of badness, which they

turn against both themselves, in rituals and assertions of selfdeprecation

and impurity, and others, by demonizing them as

impure and unrighteous. Such feelings of shame and humiliation

may further provoke intense feelings of hostility, which can

then also be discharged against the demonized others either in

WHY DOES RELIGION TURN VIOLENT? 187

fantasies of apocalyptic destruction or, if they grow more intense,

in actual terroristic deeds of world purification.

My suggestion in this paper is that universal religious

themes such as purification or the search for reunion with the

source of life can become subsumed into unconscious dynamics

such as splitting and a Manichean dichotomizing of the world

into all-good, all-evil camps, or into the drive to connect with

and appease a humiliating or persecuting idealized patriarchal

other. The result is the psychological preconditions for religiously

sponsored terrorism and violence.

NOTES

1. Neutral designations are almost impossible here. Muslims, even those who

reject the appeal to martyrdom, reject the designation of "suicide bombers,"

since these individuals have none of the psychological characteristics of

those who commit suicide, and, furthermore, suicide is condemned in the

Koran. While I regard them as terrorists, and as hard as it is for me personally,

I feel that stance should not dominate a scholarly text. I will follow the

convention of Raphael Israeli (quoted in Strenski, 2003) and refer to them

most frequently as "human bombers."

2. Examples of this assertion are found throughout, the works by Davis (2003)

and Hassan (2001). Post et al. (2003) conclude that, in contrast to the West,

in Middle Eastern Muslim communities "liberation and religious freedom

are the values that define success, not necessarily academic or economic

success" (p. 175).

3. Ruth Stein (Stein, n.d.-b, p. 6) proposes a very helpful model of a linear

progression of psychological stages in the process of transforming sacrifice

into suicidal terrorism:

1. Stage 1 involves the differentiation of the pure from the impure and a

desire to safeguard what is holy and pure.

2. Stage 2 is the elicitation of more vigorous activity, for example, more rigid

adherence to ritual, if the need to separate the pure from the impure

grows more intense. This may intensify into attempts to go beyond segregating

the impure and unholy to eliminating them, violently if necessary.

Here the wish to please God and the wish to kill begin to merge.

3. Stage 3 represents the transition of this attitude into martyrdom, where

one not only sacrifices the enemies of God but also seeks to purify oneself

by self-sacrifice as well.

4. In a series of papers, Ruth Stein has proposed that the tie to an idealized

and overpowering or persecutory object results in a psychological state that

she describes as "the libidinal and perverted relations between a certain kind

of believer and his God, in which the libidinal and the violent come together"

(Stein, n.d.-b, p. 6). Stein calls this "vertical desire," which is

188 JAMES W. JONES

the mystical longing for merger with the idealized abjecting Other. On this view

the starkly opposing terms and polarizations with which fundamentalist thinking

is suffused come to assume positions of higher and lower. . . . Fundamentalism is

not only a psychic mode of separation; it is also a psychic mode of inequality. . . .

Fundamentalism is about inequality . . . [including] the believer's inequality to

God." (p. 10)

Stein is proposing that religiously motivated terrorism is motivated by love,

not hate—love and the concomitant desire for union with an abjecting primal

father, under the guise of a god. So if religious terrorism is regression,

it is a regression to the primal father, not the primal mother. She also argues

that violent religiosity demonstrates a process "involving transformations of

hatred (and self-hatred) into idealizing love, whereby a persecutory inner

object becomes an exalted one." Thus "coercive fundamentalism is based on

a violent, homo-erotic, self-abnegating father-son relationship" (p. 10). There

is little overt expression of self-hatred in the recorded interviews with religious

terrorists. However, given the extreme judgmentalism and intense superego-

driven morality in many religious terrorists, it is reasonable to suggest

that masochism and self-hatred may lurk below the surface. Stein is

arguing that fundamentalist religion transforms this masochistic self-hatred

into a love for the father God who calls on devotees to hate and despise

themselves.

Based on his research into the psychodynamics of the Nazi movement in

Germany, Richard Koenigsberg (1975) argues that terrorism and genocide

arise from a devotion to an idealized, absolute, and psychologically omnipotent

object, be it the state, god, the party, and the like. (Copies of Koenigsberg's

other relevant papers are available from Psy.BC online.)

In another place (Jones, 2002), I have argued that the same dynamic can

be found in Otto's (1958) classic text,

The Idea of the Holy. Otto's description

of the holy as a "mysterium tremendum" carries this same sense of an overwhelming

and overpowering presence to which we can only submit ourselves.

In different ways, then, Stein, Koenigsberg, and I agree that an idealized,

absolutized, and humiliating or persecuting Other is implicated in acts

of religiously motivated terrorism and genocide.

REFERENCES

Abi-Hashem, N.

(2004). Peace and war in the Middle East. In F. Moghaddam

& A. Marsella, eds.,

Understanding terrorism (pp. 64–90). Washington, DC:

American Psychological Association.

Altemeyer, B., & Hunsberger, B.

(1992). Authoritarianism, religious fundamentalism,

quest, and prejudice.

Internat. J. Psychology Religion, 2:113–134.

Atran, S.

(2003). Genesis of suicide terrorism. Science, 229(5612):1534–1539.

Atta, M.

(n.d.). Last letter. Available from Reuters News Service, dated September

28, 2001.

Bandura, A.

(2004). The role of selective moral disengagement in terrorism

and counterterrorism. In F. Moghaddam & A. Marsella, eds.,

Understanding

terrorism

(pp. 121–150). Washington, DC: American Psychological Association.

WHY DOES RELIGION TURN VIOLENT? 189

Brokaw, B., & Edwards, K.

(1994). There is a relationship of god image to

level of object relations development.

Journal of Psychology and Theology,

22

(4):352–371.

Davis, J.

(2003). Martyrs: Innocence, vengeance and despair in the Middle East. New

York: Palgrave.

Durkheim, E.

(1965). The elementary forms of the religious life (J. Swain, trans.).

New York: Free Press.

Fairbairn, W.R.D.

(1952). The repression and return of bad objects. Psychoanal.

Studies Pers

(pp. 59–81). London: Tavistock.

Freud, S.

(1913). Totem and taboo. New York: Norton, 1950.

Gilligan, J.

(1996). Violence. New York: Random House.

Hassan, N.

(2001, November). An arsenal of believers. The New Yorker, pp.

36–41.

Jones, J.

(1991). Contemporary psychoanalysis and religion: Transference and transcendence,

New Haven, CT: Yale University Press.

(1996).

Religion and psychology in transition: Psychoanalysis, feminism and

theology.

New Haven, CT: Yale University Press.

(2002).

Terror and transformation: The ambiguity of religion in psychoanalytic

perspective.

London: Routledge.

Juergensmeyer, M.

(2000). Terror in the mind of God. Berkeley: University of

California Press.

Kimball, C.

(2002). When religion becomes evil. San Francisco: Harper San Francisco.

Kirkpatrick, L., Hood., R., & Hartz, G.

(1991). Fundamentalist religion conceptualized

in terms of Rokeach's theory of the open and closed mind.

Res. Soc. Scientific Study Religion, 3

:157–179.

Kisala, R., & Mullins, M.

(2001). Religion and social crisis in Japan: Understanding

Japanese society through the Aum affair.

New York: Palgrave.

Koenigsberg, R.

(1975). Hitler's ideology: A study in psychoanalytic sociology. New

York: Library of Social Science.

Lawrence, B.

(1989). Defenders of God. San Francisco: Harper & Row.

Lifton, R.

(2000). Destroying the world to save it. New York: Henry Holt.

MacKaw, M.

(2001). When prophecy fails: The response of members to the

crisis. In R. Kisala & M. Mullins, eds.,

Religion and social crisis in Japan (pp.

179–209). New York: Palgrave.

Marty, M., & Appleby, R.

(1994). Fundamentalisms observed. Chicago: University

of Chicago Press.

McNish, J.

(2004). Transforming shame. Binghamton, NY: Haworth.

Miller, W.

(1993). Humiliation and other essays on honor, social discomfort, and

violence.

Ithaca, NY: Cornell University Press.

Moghaddam, F.

(2005). The staircase to terrorism: A psychological exploration.

Amer. Psycholog., 60

(2):161–169.

& Marsella, A.

(2004). Understanding terrorism. Washington, DC: American

Psychological Association.

Otto, R.

(1958). The idea of the holy (J. W. Harvey, trans.). New York: Oxford

University Press.

Pattison, S.

(2000). Shame: theory, therapy, theology. Cambridge, UK: Cambridge

University Press.

Post, J., Sprinzak, E., & Denny, L.

(2003). The terrorists in their own words:

190 JAMES W. JONES

Interviews with 35 incarcerated Middle Eastern terrorists."

Terrorism Polit.

Violence, 15

(1):171–184.

Reader, I.

(1996). A poisonous cocktail: Aum Shinrikyo's path to violence. Copenhagen:

Nias.

(2000).

Religious violence in Contemporary Japan: The case of Aum Shinrikyo.

London: Curzon Press.

Spear, K.

(1994). Conscious and preconscious god representations: An object

relations perspective. Unpublished doctoral dissertation, Fuller Theological

Seminary, Pasadena, CA.

Shimazono, S.

(2001). The evolution of Aum Shinrikyo as a religious movement.

In R. Kisala & M. Mullins, eds.,

Religion and social crisis in Japan (pp.

19–51). New York: Palgrave.

Stein, R.

(n.d.-a). Evil as love and as liberation: The mind of a suicidal religious

terrorist

. Unpublished paper used with permission of the author and available

from Psy.BC online.

(n.d.-b).

Fundamentalism, father and son, and vertical desire. Unpublished

paper used with permission of the author and available from Psy.BC online.

Strenski, I.

(2003). Sacrifice, gift, and the social logic of Muslim "human

bombers."

Terrorism Polit. Violence, 15(3):1–34.

Strozier, C.

(1994). Apocalypse: On the psychology of fundamentalism in America.

Boston: Beacon.

Victoroff, J.

(2005). The mind of the terrorist: A review and critique of psychological

approaches.

J. Conflict Resolution, 49(1):3–42.

Waller, J.

(2002). Becoming evil. New York: Oxford University Press.

Watanabe, M.

(n.d.). Salvation and violence: Two dinds of salvation in Aum

Shinrikyo.

(1998). Religion and violence in Japan today: A chronological and doctrinal

analysis of Aum Shinrikyo.

Terrorism Polit. Violence, 10(4):88–100.

(2005). Aum Shinrikyo. In

Encyclopedia of Religion (2nd ed.). New York:

Thomson-Gale, Macmillan.

Wessinger, C.

(2000). How the millennium comes violently. New York: Seven

Bridges Press.

The Psychoanalytic Review

Vol. 93, No. 2, April 2006

Oceanview Towers #30

510 Ocean Avenue

Long Branch, NJ 07740

E-mail: jwj

@rci.rutgers.edu


#118 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Thu Dec 11, 2008 4:26 pm
Subject:: Top 10 Medical Breakthroughs
ashutos2
Offline Offline
Send Email Send Email
 
1. First Neurons Created from ALS Patients
 
 
 
 
Mauricio Lima / AFP / Getty

President-elect Obama has pledged to lift the seven-year ban on federal funding for embryonic stem-cell research — a boon for the field. But for some scientists, it almost doesn't matter. Researchers at Harvard and Columbia reported a milestone experiment in July, using a new method — one that doesn't require embryos at all — to generate the first motor neurons from stem cells in two elderly women with Lou Gehrig's disease, or ALS. The technique, developed by Kyoto University scientist Shinya Yamanaka in 2006, involves reprogramming a patient's ordinary skin cells to behave like stem cells, then coaxing them into the desired tissue-specific cells. Using the motor neurons created from ALS patients, scientists can now study the progress of the disease as the affected cells develop, degenerate and die in a dish — something researchers could never do before for such slow-moving conditions. Once scientists understand the development of ALS, they may be able to create more effective treatments, or perhaps even a cure.







 

.



#117 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Mon Dec 8, 2008 4:50 pm
Subject:: RSNA: Dysfunctional Prefrontal Cortex May Preserve Bad Memories
ashutos2
Offline Offline
Send Email Send Email
 

RSNA: Dysfunctional Prefrontal Cortex May Preserve Bad Memories

By Kristina Fiore, Staff Writer, MedPage Today
Published: December 03, 2008
Reviewed by Zalman S. Agus, MD; Emeritus Professor
University of Pennsylvania School of Medicine.
Click here to rate this report
http://www.medpagetoday.com/MeetingCoverage/RSNA/12008

Use this code to embed video on your website or blog:
CHICAGO, Dec. 3 -- Patients with stress-related psychiatric disorders sometimes have difficulty suppressing traumatic memories, researchers said here.

The culprit may be a dysfunctional prefrontal cortex, Nivedita Agarwal, M.D., of the University of Udine in Italy, said at the Radiological Society of North America meeting.

"There is a circuitry that helps us to forget," Dr. Agarwal said. "It's been suggested that the prefrontal cortex … can suppress the hippocampus, which stores memory."

Through functional MRI imaging, the researchers found that activity in the prefrontal cortex of psychiatric patients was significantly reduced when performing memory retrieval and suppression tasks, compared with healthy controls.

They conducted a study of 38 patients with a depressive disorder (11 with major depression, 13 with generalized anxiety disorder, nine with panic attacks, five with borderline personality disorder) and 21 healthy controls.
Action Points  
  • Explain to interested patients that a dysfunctional prefrontal cortex may prevent psychiatric patients from being able to properly suppress traumatic memories.

  • Note that this study was published as an abstract and presented orally at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal.

All of the participants reported suffering various degrees of stressful traumatic events, such as sexual or physical abuse or difficult relationships, at some point in their lives.

Each underwent an fMRI while performing a "think/no-think" memory test, which consisted of a review of word pairs. Later, after being presented with a word from each pair, they were asked to either recall or suppress the memory of the associated word.

The researchers monitored activation of both the prefrontal cortex and the hippocampus as partcipants performed these activities.

They found much more activation in all areas of the brain in psychiatric patients when they were asked to retrieve and suppress words, compared with controls.

"[Patients] are using a lot of effort to perform the task compared with healthy controls," Dr. Agarwal said.

When the researchers focused on activity in the prefrontal cortex, there was activation among patients when asked to retrieve the word, but not to the extent that was seen in controls.

When patients had to suppress the word, there was little activation in the prefrontal cortex among patients, compared with controls.

There was also a trend towards greater activation during the suppression phase in the hippocampus of patients, while controls showed greater activation during the retrieval phase.

"[Patients] keep thinking about the associated word even if they're trying not to think about it," Dr. Agarwal said.

Dr. Agarwal noted that the method holds certain clinical implications, because possible treatments exist -- such as transcranial magnetic stimulation -- that can activate neurons in the prefrontal cortex.

She concluded that memory suppression in patients is due to the dysfunctional prefrontal cortex, and that fMRI imaging holds promise for investigating transient cognitive functions in small brain areas.

Robert Zimmerman, M.D., of Weill Cornell Medical College in New York, said looking at small brain areas with fMRI has a number of important clinical implications, including testing antidepressants and other new drugs.

"Imaging is now being used routinely, so we have a way of testing a large number of patients," Dr. Zimmerman said. "The hope is that with the use of imaging like this, we'll have a purer marker [of disease activity]."


Primary source: Radiological Society of North America meeting
Source reference:
Agarwal N, et al "Mechanisms of memory suppression in stress-related psychiatric disorders: A functional magnetic resonance study" RSNA 2008; Abstract SSQ15-01.
Complete RSNA Coverage

#116 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Nov 30, 2008 4:51 am
Subject:: pharmaceuticals role in research
ashutos2
Offline Offline
Send Email Send Email
 

Research Center Tied to Drug Company

Date Published: 2008-11-24 00:00

Author: GARDINER HARRIS

Source: The New York Times


original article: http://www.nytimes.com/2008/11/25/health/25psych.html?_r=1&pagewanted=allDr. Joseph Biederman covered up drug money, says Congress

When a Congressional investigation revealed in June that Dr. Joseph Biederman, a world-renowned child psychiatrist, had earned far more money from drug makers than he had reported to his university, he said that his interests were "solely in the advancement of medical treatment through rigorous and objective study."

Court documents reveal that Dr. Joseph Biederman, a renowned child psychiatrist, pushed Johnson & Johnson to fund a research center whose goal was "to move forward the commercial goals of J&J."

But e-mail messages and internal documents from Johnson & Johnson made public in a court filing reveal that Dr. Biederman pushed the company to finance a research center at Massachusetts General Hospital, in Boston, with a goal to "move forward the commercial goals of J.& J." The documents also show that the company prepared a draft summary of a study that Dr. Biederman, of Harvard, was said to have written.

Dr. Biederman's work helped to fuel a fortyfold increase from 1994 to 2003 in the diagnosis of pediatric bipolar disorder and a rapid rise in the use of powerful, risky and expensive antipsychotic medicines in children.

Although many of his studies are small and often financed by drug makers, Dr. Biederman has had a vast influence on the field largely because of his position at one of the most prestigious medical institutions.

Massachusetts General said in a statement Monday that it took the accusations related to the research center "very seriously" and intended "to investigate these issues thoroughly."

Johnson & Johnson makes a popular antipsychotic medicine called Risperdal, or risperidone. More than a quarter of its use is in children and adolescents.

Last week, a panel of federal drug experts said that medicines like Risperdal were being used too cavalierly in children and that regulators must do more to warn doctors of their substantial risks. Other popular antipsychotic medicines, also referred to as neuroleptics, are Zyprexa, made by Eli Lilly; Seroquel, made by AstraZeneca; Geodon, made by Pfizer; and Abilify, made by Bristol-Myers Squibb.

Thousands of parents have sued AstraZeneca, Eli Lilly and Johnson & Johnson, claiming that their children were injured after taking the medicines; they also claim that the companies minimized the risks of the drugs.

As part of the lawsuits, plaintiffs' lawyers have demanded millions of documents from the companies. Nearly all have been provided under judicial seals, but a select few that mentioned Dr. Biederman became public after plaintiffs' lawyers sought a judge's order to require Dr. Biederman to be interviewed by them under oath.

In a motion filed two weeks ago, lawyers for the families argued that they should be allowed to interview Dr. Biederman under oath because his work had been crucial to the widespread acceptance of pediatric uses of antipsychotic medicines. To support this contention, the lawyers included more than two dozen documents, among them e-mail messages from Johnson & Johnson that mentioned Dr. Biederman. A judge has yet to rule on the request.

The documents offer an unusual glimpse into the delicate relationship that drug makers have with influential doctors.

In a November 1999 e-mail message, John Bruins, a Johnson & Johnson marketing executive, begs his supervisors to approve a $3,000 check to Dr. Biederman as payment for a lecture he gave at the University of Connecticut.

"Dr. Biederman is not someone to jerk around," Mr. Bruins wrote. "He is a very proud national figure in child psych and has a very short fuse."

Mr. Bruins wrote that Dr. Biederman was furious after Johnson & Johnson rejected a request that Dr. Biederman had made for a $280,000 research grant. "I have never seen someone so angry," Mr. Bruins wrote. "Since that time, our business became non-existant (sic) within his area of control."

Mr. Bruins concluded that unless Dr. Biederman received a check soon, "I am truly afraid of the consequences."

A series of documents described the goals behind establishing the Johnson & Johnson Center for the study of pediatric psychopathology, where Dr. Biederman serves as chief.

A 2002 annual report for the center said its research must satisfy three criteria: improve psychiatric care for children, have high standards and "move forward the commercial goals of J.& J.," court documents said.

"We strongly believe," the report stated, "that the center's systematic scientific inquiry will enhance the clinical and research foundation of child psychiatry and lead to the safer, more appropriate and more widespread use of medications in children.

"Without such data, many clinicians question the wisdom of aggressively treating children with medications, especially those like neuroleptics, which expose children to potentially serious adverse events."

A February 2002 e-mail message from Georges Gharabawi, a Johnson & Johnson executive, said Dr. Biederman approached the company "multiple times to propose the creation" of the center. "The rationale of this center," the message stated, "is to generate and disseminate data supporting the use of risperidone in" children and adolescents.

Documents show that Johnson & Johnson gave the center $700,000 in 2002 alone. Massachusetts General said in its statement on Monday that grant agreements indicated the center "was for scientific and educational purposes only and not for purposes of promoting, directly or indirectly, the products of Johnson & Johnson and its affiliates."

A statement Monday from Janssen Pharmaceutica, a unit of Johnson & Johnson, said it helped finance the research center in 2002 "with an objective to conduct rigorous clinical trials to clarify appropriate use and dosing of Risperdal in children."

A June 2002 e-mail message to Dr. Biederman from Dr. Gahan Pandina, a Johnson & Johnson executive, included a brief abstract of a study of Risperdal in children with disruptive behavior disorder. The message said the study was intended to be presented at the 2002 annual meeting of the American Academy of Child and Adolescent Psychiatry.

"We have generated a review abstract," Dr. Pandina wrote, "but I must review this longer abstract before passing this along."

One problem with the study, Dr. Pandina wrote, is that the children given placebos and those given Risperdal both improved significantly. "So, if you could," Dr. Pandina added, "please give some thought to how to handle this issue if it occurs."

The draft abstract that Dr. Pandina put in the e-mail message, however, stated that only the children given Risperdal improved, while those given placebos did not. Dr. Pandina asked Dr. Biederman to sign a form listing himself as the author so the company could present the study to the conference, according to the message.

"I will review this morning," responded Dr. Biederman, according to the documents. "I will be happy to sign the forms if you could kindly send them to me." The documents do not make clear whether he approved the final summary of the brief abstract in similar form or asked to read the longer report on the study.

Drug makers have long hired professional writers to compose scientific papers and then recruited well-known doctors to list themselves as the author. The practice, known as ghostwriting, has come under intense criticism recently, and medical societies, schools and journals have condemned it.

In June, a Congressional investigation revealed that Dr. Biederman had failed to report to Harvard at least $1.4 million in outside income from Johnson & Johnson and other makers of antipsychotic medicines.

In one example, Dr. Biederman reported no income from Johnson & Johnson for 2001 in a disclosure report filed with the university. When asked by Senator Charles E. Grassley, an Iowa Republican who is leading the Congressional inquiry, to check again, Dr. Biederman said he had received $3,500. But Johnson & Johnson told Mr. Grassley that it paid $58,169 to Dr. Biederman in 2001.

A Harvard spokesman, David J. Cameron, said Monday that the university was still reviewing Mr. Grassley's accusations against Dr. Biederman. Mr. Cameron added that the university had not seen the drug company documents in question and that it was not directly involved in the child psychiatry center at Massachusetts General.

Calls to Dr. Biederman were not returned.

- end -


#115 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Wed Nov 26, 2008 4:32 pm
Subject:: A New Face for A.D.H.D., and a Debate
ashutos2
Offline Offline
Send Email Send Email
 
http://www.nytimes.com/2008/11/25/health/25well.html?_r=1&ei=5070&emc=eta1

A New Face for A.D.H.D., and a Debate

Published: November 24, 2008

When pediatricians diagnose attention deficit hyperactivity disorder, they often ask their patients whether they know anybody else with the problem.

Skip to next paragraph
Stuart Bradford

Related

Health Guide: A.D.H.D. »

Well

Join the discussion about A.D.H.D.

Go to Well »

These days, children are likely to reply with a household name: Michael Phelps, the Olympic superstar, who is emerging as an inspirational role model among parents and children whose lives are affected by attention problems.

"There is a tremendous, tremendous amount of pride — I got the impression sometimes that some of the kids felt like they owned Michael," said Dr. Harold S. Koplewicz, director of the Child Study Center at New York University Langone Medical Center. "There is a special feeling when someone belongs to your club and the whole world is adoring him."

But the emergence of a major celebrity with attention deficit has revealed a schism in the community of patients, parents, doctors and educators who deal with the disorder. For years, these people have debated whether it means a lifetime of limitations or whether it can sometimes be a good thing.

Children with the disorder typically have trouble sitting still and paying attention. But they may also have boundless energy and a laserlike focus on favorite things — qualities that could be very helpful in, say, an Olympic athlete.

For that reason, some doctors are pushing for a new view that focuses on the potential strengths of the disorder. Dr. Edward M. Hallowell, a psychiatrist and author whose books include "Driven to Distraction: Recognizing and Coping With Attention Deficit Disorder From Childhood Through Adulthood" (Touchstone, 1995), says the current "deficit-based medical model" of the disorder results in low-self esteem.

"It's not an unmitigated blessing, but neither is it an unmitigated curse, which is usually the way it's presented," said Dr. Hallowell, who has the disorder himself. "I have been treating this condition for 25 years and I know that if you manage it right, this apparent deficit can become an asset. I think of it as a trait and not a disability."

The notion that a disability can be harnessed in a positive way is not a new concept. Last year, a study found that 35 percent of the small-business entrepreneurs surveyed identified themselves as dyslexic. The researchers concluded that dyslexia made them better communicators and problem solvers, more likely to delegate authority.

Dr. Hallowell says low-self esteem and low expectations result from the way the A.D.H.D. diagnosis is presented to children, parents and teachers. He tells children with attention deficit that they have the brain of a race car, and he wants to work with them to build better brakes.

"We want to tell children, 'You've got a difference, but not a disease,' " he said. "Michael Phelps is one of any thousands of examples of mega-successful people, C.E.O.s and brain surgeons and famous writers, inventors and entrepreneurs, who have A.D.H.D."

Other experts, however, say that while such success stories can be inspiring, parents need to know that their children face real risks. Research shows that children with attention deficit have different brain patterns from other children, and that they are more likely to drop out of school, be involved in car accidents and use illicit drugs.

"This reframing A.D.H.D. as a gift, personally I don't think it's helpful," said Natalie Knochenhauer, founder of A.D.H.D. Aware, an advocacy group in Doylestown, Pa. "You can't have a disability that needs to be accommodated in the classroom, and also have this special gift. There are a lot of people out there — not only do their kids not have gifts, but their kids are really struggling."

Ms. Knochenhauer, who has four children with the disorder, says they too were inspired by the astonishing performance of Mr. Phelps in Beijing. But she added, "I would argue that Michael Phelps is a great swimmer with A.D.H.D., but he's not a great swimmer because he has A.D.H.D."

Dr. Koplewicz, of N.Y.U., agreed. "There are lots of children in the world who have chronic illnesses or disorders like diabetes, allergies or dyslexia who accomplish great things in spite of the fact that they have these disorders," he said. "I worry when we say A.D.H.D. is a gift, that this minimizes how real it is."

Michael Phelps's mother, Deborah Phelps, says she has spoken openly about her son's diagnosis because she wants other parents to seek out resources and support. Her son stopped taking A.D.H.D. medication at age 10. But today, Ms. Phelps is a national spokeswoman for McNeil Pediatrics, which makes the attention-deficit drug Concerta. (Dr. Hallowell and Ms. Knochenhauer have also consulted for McNeil; Dr. Koplewicz has no industry ties.)

Ms. Phelps, who is a school principal in Baltimore, says the qualities that often accompany the disorder are not always negative, although it may require extra effort and knowledge to help children harness their talents.

"You'll find they are creative children," she said. "They do have determination when you are able to work with them and be consistent. I want young parents to reach out and get assistance and not give up hope."


#114 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Fri Nov 21, 2008 3:14 am
Subject:: NYTimes.com: A Call for Caution in the Rush to Statins
ashutos2
Offline Offline
Send Email Send Email
 


The New York Times E-mail This
This page was sent to you by:  bhat.sudhakar@...

HEALTH   | November 18, 2008
Well:  A Call for Caution in the Rush to Statins
By TARA PARKER-POPE
Is it time to put cholesterol-lowering statin drugs in every medicine cabinet?
 
 


 


 
A Call for Caution in the Rush to Statins
Stuart Bradford

Published: November 17, 2008

Is it time to put cholesterol-lowering statin drugs in every medicine cabinet?

Skip to next paragraph

Related

Health Guide: Cholesterol »

Well

Should more people be taking statins? Join the discussion.

Go to Well »

Audio

David Corcoran, a science editor, explores some of the topics addressed in this week's Science Times.

 This Week's Podcast

RSS Feed

Judging by recent headlines, you might think so. Last week heart researchers reported that millions of healthy people could benefit from taking statins even if they don't have high cholesterol.

Although many doctors hailed the study as a major breakthrough, a closer look at the research suggests that statins (like Crestor, from AstraZeneca, and Lipitor, from Pfizer) are far from magic pills. While they clearly save lives in people with a previous heart attack or other serious heart problems, for an otherwise healthy person the potential benefit remains small.

Many doctors who believe in using statins for heart disease say they needn't be given to healthy patients. Instead, they say, the focus should remain on encouraging healthful behavior and screening for traditional risk factors like high blood pressure and cholesterol.

"Statins have many biological effects that appear to be quite meaningful," said Dr. Valentin Fuster, director of the heart program at Mount Sinai Medical Center in Manhattan and past president of the American Heart Association. "But I don't think the answer is a magic drug to prevent disease. The answer is to change behavior."

Still, the latest study, called Jupiter, is sure to fuel interest in a blood test for something called C-reactive protein, or CRP. The test, which can cost $20 to $50, measures inflammation. Studies have shown that patients with high CRP are at higher risk for heart attack, even if they have normal cholesterol.

The researchers sought out men 50 and older and women 60 and older who had elevated CRP but not high cholesterol. The goal was to determine whether statins could improve their health.

But of nearly 90,000 people who were screened, only 17,802 were selected. That means 80 percent of the recruits were excluded for a variety of reasons — another inflammatory condition like arthritis, medication use, high blood pressure, a history of cancer and so on.

"If you extrapolate that, it means there are not all that many people exactly like those who were studied," said Dr. Nieca Goldberg, director of the women's heart program at New York University Langone Medical Center.

"But I can see a lot of people will be wanting a CRP test," she went on. "My greatest concern is that there will be many people who don't fit the criteria of the study, but based on this they will get blood tests and statin therapy."

And because of the way the Jupiter results were reported, many healthy people are likely to get an exaggerated view of statins' benefits. While the investigators reported an impressive-sounding 50 percent reduction in the risk of serious heart problems among the statin users, in reality everyone in the study had a low risk to begin with.

Only 1.8 percent of the subjects who took a placebo had a major cardiovascular problem during the study period. Among statin users, 0.9 percent did. In other words, the absolute risk of a serious cardiovascular problem (as opposed to the relative risk) was reduced by less than one percentage point.

"Absolute differences in risk are more clinically important than relative reductions in risk in deciding whether to recommend drug therapy," The New England Journal of Medicine noted in an editorial accompanying a report on the study.

An important indicator of the usefulness of a drug is the "number needed to treat," a measure of how many people needed to take a pill for just one person to be helped. There is disagreement about what Jupiter showed. The New England Journal editorial concluded that treating 120 people for about two years would help one person. The study authors, using different criteria, came up with a figure of 95.

Some researchers think the number is actually much lower. Extrapolating the data to five years, the study's authors concluded that just 25 healthy people would need to take a statin to prevent one serious heart problem.

As a result, some doctors say they will start testing for CRP and will offer statin therapy to patients whose levels are high.

"This was definitely a pretty stunning result," said Dr. Steven E. Nissen, chairman of cardiovascular medicine at the Cleveland Clinic. "I, for one, will be checking CRP in more patients. If it's elevated, we will be treating them."

Doctors said one worrisome trend did emerge in the study. In the statin group, 3 percent of the people developed diabetes during the study period, compared with 2.4 percent in the placebo group.

Moreover, because the study was stopped early (so those in the placebo group could begin taking statins for their presumed heart benefits), it did not yield much insight into the drugs' long-term safety. Nor is it clear that the early benefit shown in the statin group would have held up over a longer period or whether other risks might have emerged.

"This study does not indicate that we should be putting statins in the drinking water or fortifying cereal with statins," said Dr. Goldberg, of N.Y.U. "There are millions of people who haven't gone in and even gotten their cholesterol checked, but everybody wants the new thing. They want to believe the new thing will be the total answer."

 
.



#113 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Thu Nov 20, 2008 4:32 pm
Subject:: Fwd: IndianPsychiatrists - ‘Atheism is another way of practising spirituality’!
ashutos2
Offline Offline
Send Email Send Email
 





Brahmin priest punished for Muslim kid care
Sumanta Ray Chaudhuri
Thursday, November 20, 2008  03:53 IST

http://www.dnaindia.com/report.asp?newsid=1208036

 
KOLKATA: A Brahmin priest was made to atone for inviting a Muslim kid to his house for dinner. The Trinamool Congress village panchayat humiliated the 50-year-old priest in public.

They made him and his family undergo a ritual cleansing bath and then made him cut nails of his family members. They next asked him to shave his head, but he refused.

Lakshmikanta Chakrabarti, a Brahmin priest at Chandramer village in West Bengal's East Midnapore district, is very fond of Sheikh Chottu, a Muslim orphan who works at a garment factory near his house.

Chottu being his son Shankar's friend, he got to meet him more often. The friendship was not objected to, but elected representatives of the village panchayat did not appreciate the priest inviting the kid for dinner.

Panchayat deputy chief Adhikari and panchayat member Narayan Chandra Maiti summoned Chakrabarti to an open court and ordered him to atone. They made him take a cleansing dip with his family and cut their nails.

Chakrabarti obeyed to save his job. The panchayat  next ordered him to shave his head. But the old priest would yield no more. So the panchayat leaders ordered boycott of his priestly services at the local temple and at individual houses.

Chakrabarti approached the police but no help was given. The police now claim ignorance about the whole incident. Senior Trinamool Congress leaders promised help but nothing has been done yet.

Their aloofness, however has only served to strengthen Chakrabarti's resolve. "If necessary, I will leave my house with my family and take shelter on roads," he said.
Panchayat member Trilochon Gorai said he had heard of the incident but was not sure if it was true. "I will look into it. In all probability it is a conspiracy to malign our members," he said.

2008/11/18 nichana ashok <drashokn@...>

Note: forwarded message attached.

Add more friends to your messenger and enjoy! Go to http://messenger.yahoo.com/invite/



---------- Forwarded message ----------
From: "ashokkumar nichanametla" <ashokndr@...>
To: psychiatryloversindia@yahoogroups.com, e_ips@yahoogroups.com
Date: Tue, 18 Nov 2008 07:35:11 +0530
Subject: [psychiatryloversindia] 'Atheism is another way of practising spirituality'!-can psychiatry exist without spirituality?

'Atheism is another way of practising spirituality'

Font Size
Nadine Kreisberger Posted: Sep 09, 2007 at 1742 hrs IST

R



Dominique Girard, French Ambassador to India.

What does Spirituality mean to you?
I have a great deal of distrust for religion and in the West, we often equate religion with spirituality. Indeed, I was born and raised Catholic but when I grew up and discovered the unfairness of the world, I rejected it all: how could all this evil and God coexist? Yet, philosophical and metaphysical questioning about life and its meaning has been central to me. It is just that God faded out of the picture. Being an atheist is just another way of practising spirituality.

Ads By Google

Do you believe you are guided and protected by a superior force?
I do not believe in an external force; rather I believe that all the phenomena of guidance, intuition, parapsychological occurrences and so on are a reflection, an echo of the complexity of our minds. I believe in an evolution and a continuity from bacteria to animals to humans, driven by a fantastic force of life.

Do you believe you have a special mission or purpose in this life?
The New Testament has this parable of talents, which tells of children receiving many gold coins in inheritance. Their duty is not to misuse them and use them as meant to. So indeed, there is a purpose to life or a duty, which in moral or metaphysical terms is that if given a lot, you must give back as well. It is like drawing a balance sheet in the intimacy of my mind and seeing if the bottomline is positive or not.

What is spirituality for you in your day-to-day life?
Buddhism is the philosophical approach which fits best my thinking and it recommends that one constantly question everything, including the need to question itself. So I guess that this love of scepticism, this permanent questioning is my day-to-day life approach: no master, no guru, always trying to find my own truth with my own judgment.

What has been the role of spirituality in your life as a diplomat?
As an ambassador, I have a number of duties. Yet, I should never be fooled by them, become completely identified with them or with the fact that I have to speak for someone else most of my life. The self, my inner compass, must remain distinct. The intellectual and spiritual muscles need to constantly be active. Otherwise I would be like an actor who would never stop acting.

What have been your main spiritual inspirations?
Of course it began with Catholicism, in which I grew up, going to church and to Sunday school. During my teenage time, I gradually rejected it and found different ways of addressing the meaning of life and other metaphysical questions. Buddhism in particular, with its basic scepticism and intellectual honesty, has seemed the most appropriate theory, providing me with fantastic instruments —like a tool-box —to both answer those questions and stay away from the excesses of all religions.

If you were to be reincarnated, what would you like to be?
I do not believe in reincarnation but I think it would be extremely exciting to see life through the eyes of a dog. Dogs have an acute mind and consciousness and more strikingly, they have a more direct access to emotions like love, faith, trust than us humans, for whom it is much more difficult to experience those feelings wholly and unconditionally.

If there were one question you could ask God, what would it be?
I would ask God how much time He will give me because I have a lot of questions to ask.

What is your idea of happiness?
It is about both possession and calm — possession of feelings, of the ability to love, of all those ways of feeling genuinely alive; and at the same time being able to face everything with inner calm. This is ultimate happiness.
The writer is a French traveller who has worked in international relations, classical music, journalism and psychology. But it is her particular interest in spiritual matters that has led her to devise this version of The Proust Questionnaire: "It helps us to see people who they really are inside."



--
Dr. N. Ashok Kumar


 
.



#112 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Wed Oct 29, 2008 3:58 pm
Subject:: Magnet for treatment of depression
ashutos2
Offline Offline
Send Email Send Email
 
 
Magnet Device Aims to Treat Depression Patients
October 21, 2008

WASHINGTON (AP) -– The government has approved the first noninvasive brain stimulator to treat depression -- a device that beams magnetic pulses through the skull. If it sounds like science-fiction, well, those woodpecker-like pulses trigger small electrical charges that spark brain cells to fire. Yet it doesn't cause the risks of surgically implanted electrodes or the treatment of last resort, shock therapy.

Called transcranial magnetic stimulation or TMS, this gentler approach isn't for everyone. The Food and Drug Administration approved Neuronetics Inc.'s NeuroStar therapy specifically for patients who had no relief from their first antidepressant, offering them a different option than trying pill after pill.

"We're opening up a whole new area of medicine," says Dr. Mark George of the Medical University of South Carolina in Charleston, who helped pioneer use of TMS in depression. "There's a whole field now that's moving forward of noninvasive electrical stimulation of the brain."

While there's a big need for innovative approaches -- at least one in five depression patients is treatment-resistant -- the question is just how much benefit TMS offers.

The FDA cleared the prescription-only NeuroStar based on data that found patients did modestly better when treated with TMS than when they unknowingly received a sham treatment that mimicked the magnet. It was a study fraught with statistical questions that concerned the agency's own scientific advisers.

For a more clear answer, the National Institutes of Health has an independent study under way now that tracks 260 patients and may have initial results as early as next year.

Quantifying the benefit is key, considering the price tag. TMS is expected to cost $6,000 to $10,000, depending on how many treatments a patient needs, says Dr. Philip Janicak of Rush University Medical Center in Chicago, who helped lead the NeuroStar study. That's far more expensive than medication yet thousands of dollars cheaper than invasive depression devices.

Neuroscientists have been using TMS for years as a research tool in brain studies. Zap a powerful magnet over a certain spot on the head -- where motion is controlled -- and someone's arm can suddenly, involuntarily, lash out. Beyond the "wow" factor, magnetized pulses were triggering brain activity.

The question was how to harness that activity in a way that might improve disease. TMS also is being studied in stroke rehabilitation and other brain disorders.

"Nobody thought this would work; it was a crazy idea. I had to do it at 6 in the morning before the real scientists came in," South Carolina's George laughs as he recalls work he began in 1993.

But, "the brain is an electrical organ," George adds, explaining the rationale. "Electricity is the currency of the brain. It's how the brain does what it does."

For depression, psychiatrists aim the magnet at the left front of the head, the prefrontal cortex. Since everyone's brain is different, they first zap the top of the head to find a patient's motor-control region, and then carefully move 5 centimeters forward. Then, the NeuroStar beams about 3,000 pulses a minute during a 40-minute treatment, done about five times a week for up to six weeks.

The theory: Stimulating brain cells in the prefrontal cortex triggers a chain reaction that also stimulates deeper brain regions involved with mood.

TMS did prove to be very safe: Patients in the NeuroStar study suffered no seizures or memory problems like shock therapy can cause, or other reactions throughout the body. The chief complaint from the sessions was headaches.

The FDA cleared the device after focusing just on a subset of the patients initially enrolled -- 164 who had failed one antidepressant during their current bout of depression, not those who were more severely treatment-resistant.

What's a modest benefit? About 24 percent who got TMS scored significantly better on standard depression measures after six weeks, compared with 12 percent who got the sham, says Janicak. That's about as well as patients respond to a single antidepressant, he says.

Some reported remarkable improvement.

"One day it was like a light switch went off," says Steve Newman, 60, of Washington, D.C., who enrolled in the NeuroStar study at the University of Pennsylvania in 2005.

Newman had suffered repeated bouts of depression since he was a teenager, and drug after drug barely blunted it. He was considering shock therapy when he heard about TMS.

After two weeks of treatment, Newman was wondering if he was getting the sham -- when suddenly, he started feeling lots better, and doctors spotted a corresponding major improvement in his depression measurements.

"I was awake. I was there," says Newman who said he still gets what he calls a "maintenance dose" of TMS about once a month.

Copyright 2008 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

.
InteliHealth
. . . .
.
More News
InteliHealth .
.
Top News
General Health
This Week In Health
Addiction
Allergy
Alzheimer's
Asthma
Arthritis
Babies
Breast Cancer
Cancer
Caregiving
Cervical Cancer
Children's Health
Cholesterol
Complementary & Alternative Medicine
Dental / Oral Health
Depression
Diabetes
Ear, Nose And Throat
Eyes
Family Health
Fitness
Headache
Heart Health
HIV / AIDS
Infectious Diseases
Lung Cancer
Medications
Men's Health
Mental Health
Nutrition News
Multiple Sclerosis
Nutrition Guide
Parkinson's
Pregnancy
Prevention
Prostate Cancer
Senior Health
Sexual / Reproductive Health
Sleep
Tobacco Cessation
STDs
Stress Reduction
Stroke
Weight Management
Today In Health History
Women's Health
Workplace Health
.
.
.
.
InteliHealth


#111 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sat Oct 18, 2008 4:49 pm
Subject:: does the key to treatment lie in stimulation and not in neuro transmitters
ashutos2
Offline Offline
Send Email Send Email
 
 
Hit a nerve to beat migraine
18 Oct 2008, 0055 hrs IST, TNN
 
MUMBAI: For 11 years, Mulund resident Tilak Lodaya (42) has put up with migraines
that left him with a pounding head for nearly five days a week. He
popped 20 pills a day and even tried botox. He visited specialists, tried ayurveda and practiced yoga, but found little relief.

When his doctors suggested that he opt for a new, albeit expensive surgical procedure to stimulate a nerve in his brain, Lodaya was more than willing to try it. "Most migraine patients get relief from medicines, but Lodaya belonged to the small segment (3 to 14 %) of people who suffer intractable headaches which don't respond to standard medicines. I attended a conference in Boston where a doctor presented how all eight of his patients with intractable migraine had responded to neuro-stimulation,'' said headache specialist Dr K Ravishankar from Jaslok Hospital at Peddar Road. Lodaya was evaluated according to the guidelines of the International Headache Society before doctors decided to put him through the procedure. "We performed an occipital nerve stimulation (ONS) procedure in which two electrodes were implanted in the brain at the back of the head,'' said head of sterotactic and functional neuro-surgery at Jaslok Hospital, Dr Paresh Doshi. He explained that the electrodes are connected to a pacemaker which can be controlled by the patient when he suffers a migraine. The stimulation helps release chemicals which increase the pain threshold of the patient.

Lodya underwent a six-hour-long procedure on Saturday. Today, he says he has got significant relief. "In this week, I've had only one episode of migraine, and I adjusted the pacemaker so I didn't feel the pain,'' he said. However, he still has to follow diet modifications like other migraine patients.

Globally, 40 patients have undergone ONS. Independent experts TOI spoke to said it was still a very new treatment and was difficult to pass a judgement on long-term outcomes. A doctor pointed out that the exorbitant cost of thetreatment (the device could cost anywhere from Rs 2.5 lakh to Rs 3.75 lakh) often put it out of reach for many.

#110 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Oct 5, 2008 2:58 pm
Subject:: Fwd: Psychoanalytic Therapy Wins Backing
ashutos2
Offline Offline
Send Email Send Email
 

 

Published: September 30, 2008

Intensive psychoanalytic therapy, the "talking cure" rooted in the ideas of Freud, has all but disappeared in the age of drug treatments and managed care.

Skip to next paragraph
Sigmund Freud Museum/Associated Press

Research is smiling on treatment rooted in Freud's ideas.

 

But now researchers are reporting that the therapy can be effective against some chronic mental problems, including anxiety and borderline personality disorder.

In a review of 23 studies of such treatment involving 1,053 patients, the researchers concluded that the therapy, given as often as three times a week, in many cases for more than a year, relieved symptoms of those problems significantly more than did some shorter-term therapies.

The authors, writing in Wednesday's issue of The Journal of the American Medical Association, strongly urged scientists to undertake more testing of psychodynamic therapy, as it is known, before it is lost altogether as a historical curiosity.

The review is the first such evaluation of psychoanalysis to appear in a major medical journal, and the studies on which the new paper was based are not widely known among doctors.

The field has resisted scientific scrutiny for years, arguing that the process of treatment is highly individualized and so does not easily lend itself to such study. It is based on Freud's idea that symptoms are rooted in underlying, often longstanding psychological conflicts that can be discovered in part through close examination of the patient-therapist relationship.

Experts cautioned that the evidence cited in the new research was still too meager to claim clear superiority for psychoanalytic therapy over different treatments, like cognitive behavior therapy, a shorter-term approach. The studies that the authors reviewed are simply not strong enough, these experts said.

"But this review certainly does seem to contradict the notion that cognitive or other short-term therapies are better than any others," said Bruce E. Wampold, chairman of the department of counseling psychology at the University of Wisconsin. "When it's done well, psychodynamic therapy appears to be just as effective as any other for some patients, and this strikes me as a turning point" for such intensive therapy.

The researchers, Falk Leichsenring of the University of Giessen and Sven Rabung of the University Medical Center Hamburg-Eppendorf, both in Germany, reviewed only those studies in which the therapy had been frequent — more than once a week in many cases — and had lasted at least a year or, alternatively, had been 50 sessions long. Further, the studies had to have followed patients closely, using strict definitions of improvement.

The investigators examined studies that tracked patients with a variety of mental problems, among them severe depression, anorexia nervosa and borderline personality disorder, which is characterized by a fear of abandonment and dark squalls of despair and neediness.

Psychodynamic therapy, Dr. Leichsenring wrote in an e-mail message, "showed significant, large and stable treatment effects which even significantly increased between the end of treatment and follow-up assessment."

The review found no correlation between patients' improvement and the length of treatment. But improve they did, and psychiatrists said it was clear that patients with severe, chronic emotional problems benefited from the steady, frequent, close attention that psychoanalysts provide.

"If you define borderline personality broadly as an inability to regulate emotions, it characterizes a lot of people who show up in clinics, whether their given diagnosis is depression, pediatric bipolar or substance abuse," said Dr. Andrew J. Gerber, a psychiatrist at Columbia. For some of those patients, Dr. Gerber said, "this paper suggests that you've got to get into longer-term therapy to make improvements last."

Some psychoanalysts were more surprised by where the paper appeared than by its results: most review papers in major medical journals have hundreds of studies to draw on, or certainly far more than 23. The new review is encouraging, they said, but also a reminder of how much more study needs to be done.

Dr. Barbara L. Milrod, a professor of psychiatry at Weill Cornell Medical College, who like Dr. Gerber is a clinical practitioner of psychodynamic therapy, said further research was crucial as a matter of survival for a valuable treatment.

"Let's be real," Dr. Milrod said. "Major medical centers have been shutting down psychodynamic training programs because there isn't an adequate evidence base."

This article has been revised to reflect the following correction:

Correction: October 3, 2008
An article on Tuesday about a review of studies of psychoanalytic therapy referred incorrectly to the 23 studies included in the review. In many of the studies — but not all of them — the therapy had been given more than once a week.

 

http://www.nytimes.com/2008/10/01/health/01psych.html?_r=3&scp=1&sq=therapy&st=cse&oref=slogin&oref=slogin&oref=slogin



#109 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Oct 5, 2008 6:08 am
Subject:: treatment of cognition in schizophrenia
ashutos2
Offline Offline
Send Email Send Email
 
Online Discussions

Updated 26 May 2008
 

Live Discussion: New Approaches to Cognition in Mental Illness


Fred Sabb

Bob Bilder

Deanna Barch

View article

View article

On 9 June 2008, at 12 noon, Eastern U.S. time, Fred Sabb and Bob Bilder of UCLA, and Deanna Barch of Washington University, St. Louis, led an online discussion focusing on two elements of the burgeoning effort to measure and treat cognitive deficits in schizophrenia—the CNTRICS initiative and the Phenowiki knowledge base. We invite you to read their background text below, and we suggest as background reading two recent papers: on CNTRICS, Carter and colleagues in Biological Psychiatry (Carter et al., 2008), and on Phenowiki, Sabb and colleagues in Molecular Psychiatry (Sabb et al., 2008). [Editor's note: We thank the Society for Biological Psychiatry and Elsevier for permission to post a full copy of the CNTRICS paper, and Molecular Psychiatry and Nature Journals for providing open access to the Phenowiki article for one month.]

References:
Carter CS, Barch DM, Buchanan RW, Bullmore E, Krystal JH, Cohen J, Geyer M, Green M, Nuechterlein KH, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R. Identifying Cognitive Mechanisms Targeted for Treatment Development in Schizophrenia: An Overview of the First Meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative. Biol Psychiatry. 2008 May 6. Copyright Society of Biological Psychiatry (2008) Abstract

Sabb FW, Bearden CE, Glahn DC, Parker DS, Freimer N, Bilder RM. A collaborative knowledge base for cognitive phenomics. Mol Psychiatry. 2008 Apr ; 13(4):350-60. Abstract

View Transcript of Live Discussion — Posted 20 September 2008

View Comments By:
Richard Walter James Neufeld — Posted 29 May 2008


Background Text
By Fred Sabb, Bob Bilder, and Deanna Barch

Over the past decade and a half there has been a growing awareness of the importance of impaired cognition in schizophrenia as a critical "glass ceiling" that limits functional outcome for people with the illness. For example, many people with schizophrenia continue to have problems with memory and problem solving, along with difficulties living and working independently, despite the fact that their hallucinations and delusions may be well controlled by their current antipsychotic medications. During the 1990s there was initial enthusiasm that second-generation antipsychotic drugs would confer significant advantages over first-generation agents for this aspect of the illness. However, it has now become clear that the data are disappointing in this regard. This understanding has resulted in a growing awareness of an urgent need for the discovery and development of new treatments for schizophrenia that will enhance cognitive functioning in the illness and improve functional outcome. In order to do so it is important to have reliable and valid measurements of cognitive function that are clearly linked to the neural systems that we would wish to target with pharmacological or psychological interventions.

Topic A—CNTRICS
The Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative was created to translate successful basic animal and human cognitive neuroscience into useful clinical research in schizophrenia. This initiative followed on the heels of the Measurement and Treatment Research to Improve Cognition in Schizophrenia program (MATRICS), which was also designed to enhance the development of treatments designed to improve cognition in schizophrenia. Because of the laudable speed with which MATRICS developed a standardized battery for use in such clinical trials, the measures selected were primarily well standardized and psychometrically sound measures stemming from traditional clinical neuropsychology approach, and not necessarily from advances in basic cognitive neuroscience. CNTRICS was designed to address this issues by facilitating and promoting research that would translate paradigms from basic cognitive neuroscience into versions useable in clinical trials.

Why might translating paradigms from cognitive neuroscience help us to design and evaluate treatments for cognitive impairment in schizophrenia? If appropriate paradigms can be translated from basic cognitive neuroscience for use in clinical trials, the opportunity for bridging translational research from "bench to bedside" may be dramatically enhanced. Currently, development of new tools in drug development has outpaced our capacity to identify the most relevant targets of treatment. Thus we have unprecedented capacity to design new molecules, but lack understanding of how these molecules impact cellular and neural systems level functions in ways that can be meaningfully related to the cognitive and symptomatic dimensions that are the ultimate hallmarks of efficacy and effectiveness.

Why is it important to use bioinformatics approaches in the design and interpretation of studies on cognitive enhancement in schizophrenia? Informatics strategies may help bridge the currently wide gap between our understanding of basic molecular mechanisms and higher level neural systems, cognitive, and syndromal dimensions. There are already major resources developed for genomics and proteomics that are revolutionizing discovery processes in these disciplines. Similar strategies are under development to link repositories of biological knowledge to higher level systems and clinical knowledge. Ultimately it will be possible to connect information about drugs, via the systems in which these drugs act, to the ultimate clinical endpoints that are used in clinical trials. Informatics systems capable of relating molecular to behavioral knowledge need major development, primarily at the behavioral level. There is increasing consensus, achieved via initiatives like MATRICS and CNTRICS, about the important dimensions of behavior and relevant measurement methods. Informatics strategies can model results of these consensus processes and the evidence that supports or conflicts with these results.

Topic B—Phenowiki

How, then, will researchers select the most appropriate paradigms? The Consortium for Neuropsychiatric Phenomics (CNP) has been developing informatics procedures and tools to assist researchers in the development of hypotheses that span multiple levels of scientific inquiry, using literature association techniques, and now also in an online knowledge-base of quantitative data from published articles. Phenowiki is the entry point for phenotype annotation for the CNP tools (Sabb et al., 2008) A concrete example is offered by the CNTRICS process, where a set of cognitive dimensions and measurement approaches has been arrived at via consensus meetings. Data supporting these decisions are now being assembled, and a collaborative knowledgebase will be used to provide an initial scaffold for entry of data regarding the reliability and validity of specific measurement methods considered most relevant to the cognitive dimensions. These data can then be subjected to modeling approaches that can help identify more clearly which paradigms, and which parameter modifications within paradigms, may best relate to specific cognitive dimensions, neural systems activity, drug effects, and diagnostic effects. This knowledgebase can support objective decision making about paradigm selection and refinement for future research.

Figure: Entrez Knowledge Base components and their current sizes and connections.

What is Phenowiki good for?

  • Annotation of quantitative data in published articles for hypothesis modeling (i.e., do people want to lay out their hypotheses with quantitative effect sizes)?
  • Connection to other knowledge bases (i.e., how important would it be to link to other Entrez components, e.g., gene, protein, SNP, OMIM, GEO…see figure)
  • Literature search/retrieval (via PubMed)?
  • Test selection?
    • Genetics research (e.g., heritability data, demonstrated genetic associations)?
    • Psychopharm research (e.g., demonstrated drug effects, reliability statistics, test durations)?
  • Meta-Analysis & Ontology development - through interaction with other CNP tools
    • Voting rights for related concepts, and class hierarchies?
    • Empirical data suggesting validity of constructs by covariance structure analysis?
  • Who might contribute?
    • Graduate students?
    • Faculty level scholars?
    • Funded consortium of annotators?
  • What incentive structures might work?
    • Burning desire to know the truth?
    • Collection of private hypotheses?
    • Publication of hypotheses (i.e., is there interest in an on-line journal of meta-analytically supported multi-level hypotheses)?


#108 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Sep 28, 2008 6:03 pm
Subject:: flower
ashutos2
Offline Offline
Send Email Send Email
 
#107 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Sep 21, 2008 6:33 pm
Subject:: articles on abuse
ashutos2
Offline Offline
Send Email Send Email
 
Emotional Abuse
 
"Sticks and stones may break my bones, but words can never hurt me!

Remember that childhood chant? Big fat lie. In fact, while physical scars can heal, emotional abuse causes scars that last - invisible - well into adulthood. In emotional abuse, the weapon is often words. This is often the hardest type of abuse to face, because of all types of abuse, it leaves no visible scars, and survivors have a hard time accepting that what they went through constituted abuse.

Answers to Common Questions About Emotional Abuse

Bully Victims: Psychological and Somatic Aftermaths

8 Styles of Controlling Parents

Emotional Abuse Effects

Neglect in Childhood

Self Esteem: The Greatest Gift You Can Give Your Child

Types of Emotional Abuse

Unsilencing Emotional Abuse

You Carry the Cure in Your Own Heart

 

Physical Abuse
 
Any physical act committed against a child, which results in a non-accidental injury, is termed physical abuse. It is often preceded by physical neglect. A neglected or ignored child will increase their attention-seeking behaviour, even if it only attracts negative attention. Children with special needs or disabilities are at greater risk of being abused because their needs put more of a demand on their parents.

Parents who physically abuse their children, were often treated in a similar manner when they were young. Also, the chances of abuse increase if the child reminds the parent of a disliked relative.

Some experts view slapping on the face as on par with sexual abuse, as the abuser is striking at the child's very identity. Also, hitting on the buttocks is harmful, as it is a highly sensitive zone in children, and these children can grow up associating pain with sexual stimulation.

Abuse and Discipline: A Comparison

Physical Abuse Common in Indian Children

Physical Abuse Indicators

Physical Abuse of Children: An Overview

When Does Physical Punishment Become Physical Abuse?

Why Punishment Does Not Work


#106 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Sep 21, 2008 6:31 pm
Subject:: abuse
ashutos2
Offline Offline
Send Email Send Email
 

Child Abuse Story
On My Own Terms, A Memoir


Darlene Barriere: Violence & Abuse Prevention EducatorOn My Own Terms, A Memoir is my child abuse story, a story that details abuse at the hands of both my mother and father. My story clearly shows the residual effects of child abuse, effects that many abuse survivors exhibit.

One of many such effects for me was morbid obesity. I ate volumes of food. I couldn't stop eating, because when I ate, I no longer had to deal with the painful memories. But the insatiable binging had its own painful effects...


Read on for an excerpt of my child abuse story . . .


From Chapter 27 - Consumption:

My weight ballooned. Queen-sized panty hose—the largest available—were no longer adequate. The graph on the cardboard packaging reflected they would fit someone 5' 10" up to 210 lbs. But now that I was two hundred forty-five pounds, the crotch of my pantyhose sat about six inches above my knees. Without protection, my inner thighs chafed and bled from constant rubbing. I slathered Vaseline on the open sores to act as a protective barrier. The neighborhood pharmacist could have cured the ailment with a special ointment, but I wouldn't risk his chiding. A feminine discharge left a thick yellow residue on my panties, which made me smell like freshly kneaded bread dough. My doctor would have given me a prescription, but I wouldn't chance his condemnation.

The bingeing escalated.

I phoned different restaurants outside my suburban boundaries to avoid facing the same deliverymen night after night. I knew if the order was too small for two people but too large for one the restaurant staff would know it was for my consumption alone. I hid this by ordering enough for a group. "Bill would probably like garlic bread with that," I told the voice on the other end of the line. "Suzy can share the noodles with Karen, and I'll have an extra large seafood salad for myself. And oh yes, a half dozen Pepsi for us to share."

I paid for the delivery with my Chargex (now Visa) card, just like I'd done every weekend since receiving the card a month before. Take-out had already absorbed almost my entire five-hundred-dollar credit limit. I placed the four containers on the end table next to the recliner, beside what was left of the pizza and Chinese food I had already ordered from two other restaurants. I tried to delay gratification by counting, but I didn't get passed five. I tore off a slice of pizza from its soggy cardboard tray and devoured it on the way to the television. Only two stations aired all night, so I turned the dial to one of them. In an hour I wouldn't be able to move, let alone get up to relieve myself. On the way to the bathroom, I reached for another slice.

In the living room again: Food. Wonderful, glorious food. I wolfed it down. And when my body fought not to swallow, I held onto the armrests of my chair to prepare my chest and stomach for the half-chewed mouthfuls. No texture. No pleasure. No taste. And as the memories resurfaced, I imprisoned them into the pit of my gut. I didn't stop until the last bite refused to be ingested. It was another night spent in my recliner.

I woke up fighting for breath. My sternum felt ready to split wide open. The gastric juices hadn't finished assimilating last night's midnight binge. There was a foul, rancid taste at the back of my throat. My inflated stomach threatened to purge its contents.

I'd stopped weighing myself at two-sixty-five. Three Mondays ago, the scale disclosed I had gained ten pounds over the weekend, the same as the weekend before. I didn't need to step on the scale today to know how much I had gained this weekend and every other weekend in between. I must be at least three hundred pounds. "I don't want to die!" I cried out.


Bookcover: On My Own Terms, A MemoirIf you'd like to read more, On My Own Terms, A Memoir is a quick and simple download. PayPal is used as a secure, authorized billing agent for your security. Your credit card is validated through PayPal´s ordering system and once payment is made, you will be re-directed to a download page. Once there, you can retrieve the book and start reading straight away.

The e-book is in PDF format (if you need it, a free PDF reader is available on the download page) with a file size of approximately 1.90 MB. Download times vary according to your Internet connection (less than 2 minutes with ADSL/Broadband).

If security is a concern to you, rest assured that a secure server is used to process your order.

Back to Child Abuse Effects Homepage from this My Child Abuse Story page


#105 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Sep 21, 2008 3:13 am
Subject:: Fwd: Lifelong Scars
ashutos2
Offline Offline
Send Email Send Email
 
 
The Survivors Network of those Abused by Priests

Psychological Effects of Abuse
Recent stories of interest

Lifelong Scars

'Victims see themselves as damaged goods,' says a therapist who has treated adults molested as children

June 14, 2004
By LISA O'NEILL HILL / The Press-Enterprise

Mark Serrano suffers anxiety attacks when adults get too close to his children. Deborah Hardeman feels her stomach churn when she smells "Old Spice." Debbie White tried to kill herself.

All were robbed of their childhoods, innocence and self-esteem by people they trusted. All were sexually molested decades ago and struggle with the consequences.

Each was abused repeatedly. Not one told anyone what was happening, which experts say is typical and illustrates a larger problem: Child sexual abuse is drastically underreported and believed to be much more widespread than any statistics or studies can show.

By conservative estimates, one in five girls and one in 10 boys will be sexually victimized before reaching adulthood, according to the National Center for Missing & Exploited Children in Virginia. That includes children who are sexually abused by strangers, relatives and family friends.

The increasing popularity of the Internet has given predators a new way to reach potential victims: About one out of every five children online is approached in a sexual way, and of those, only 25 percent tell their parents, according to the center.

Perpetrators include parents, teachers, coaches, clergy, even peace officers.

A former Riverside police officer, Adam James Brown, has been charged with sexual abuse of boys in Riverside and Wisconsin. Brown, who remains in federal custody, is among 21 men arrested in connection with a large child-sex and Internet-pornography ring. He is accused of traveling to a rural town in Wisconsin to have sex with young boys. Authorities said another defendant was paid to organize the liaisons and sold Internet images of children engaged in sex acts.

Brown has pleaded not guilty to a count of crossing state lines to engage in a sexual act with a minor.

The impact of these kinds of crimes metastasizes, scarring victims for years and leaving their parents and siblings shrouded in guilt.

"We just feel like we failed her in protecting her," said the 33-year-old aunt of a Riverside girl who was molested and kidnapped by her father's roommate.

"I think it's important that people understand there's a direct victim and all the indirect victims who have to help that person get through it."

Like the other victims, Hardeman said the long-term abuse she suffered at a young age affected every part of her life.

"I still can't believe how my life has turned out," said Hardeman, 46, of Riverside. "I'm never going to let anybody cross those boundaries again."

The abuse affected her judgment, she said. It took her years to realize she sought out people who treated her badly.

Therapists say this is common, that the scars of sexual abuse can be difficult to heal.

"Basically, it affects every aspect of their adult lives - cognitively, emotionally, interpersonally, physically," said Ann Pultz Kramer, a Moreno Valley marriage-and-family therapist who has treated victims of sexual abuse. "Psychologically, their self-esteem, self-image and identity are impaired. Victims see themselves as damaged goods."

Suppressed trauma

Serrano, 40, built his life around suppressing the trauma of sexual assaults he says were committed by his parish priest in a New Jersey rectory. He did not tell anyone what had happened until years later.

"He invested a great deal of time in stripping me of my instincts," said Serrano, a father of four who lives in northern Virginia.

"He got me into one-on-one encounters where he methodically built my confidence and a bond of secrecy between us. He disabled my mind so I didn't even debate with myself whether I should go call for help."

The priest had a robust personality, a wonderful sense of humor and easy access to children. He liked to take the children fishing and had them sleep over at the rectory on the eve of the trips, Serrano said. He said the priest had special talks with him and showered him with gifts and praise.

"He made me feel like I was 10 feet tall, like I was a uniquely special child who was the center of his attention and affection."

Serrano said the priest first showed him pornographic magazines and videos under the pretext of educating the then-9-year-old boy about sex. He gradually built up to sexual abuse, which Serrano said continued until he was 16.

"He was a master of manipulation. He was literally an evil genius dressed in priest's clothing. He didn't just fool me. He didn't just fool my parents. He fooled an entire community. Because of his position of authority, he wasn't questioned."

Serrano said his mind would drift as he was being molested.

"The trauma was too great. I recall it as if I was looking down from the scene. It's a coping mechanism," he said

The priest's breath smelled like vodka and orange juice, like the screwdriver drink he favored. To this day, the smell of alcohol on someone's breath reminds Serrano of the abuse.

After each episode of abuse, Serrano would get on his bicycle and flee. "I would rush from the scene as quickly as possible, pedaling as quickly as I could to erase the memory," he said.

Unable to cope, he became a long-distance runner. He dove into emotionally dependent relationships with girls. He worked hard in school.

He said he did not realize crimes had been committed against him until he was 20 and read a newspaper story about a priest who had been convicted of molesting a boy.

Until that point, "I knew deep in my heart it was wrong and it was bizarre and it was weird, I just didn't know it was criminal."

Serrano reported the abuse to his bishop, but nothing was done, he said.

Ten years ago, Serrano decided to take matters into his own hands: He hired a private detective to find the priest, to see if he was still molesting children.

Accompanied by his parents, Serrano knocked on the priest's door. His father wore a hidden microphone.

Serrano said he got the confirmation he sought when the priest opened the door. He saw two recliner chairs, just like the ones he had been in when he was molested.

"It was a powerful moment in my life, because I was in control of the encounter. I felt like I was in a position of power and he was not. I felt disgust, strength and empowerment."

The priest was never prosecuted, but Serrano sued the Catholic Church and settled. As part of the settlement, he signed a confidentiality agreement. He broke the pact two years ago when he told his story to The New York Times.

"Silence was probably the worst condition I could have placed on me. I delayed my own healing for 17 years. Silence and secrecy are toxic for a victim of sexual abuse," said Serrano, now a board member of Survivors Network of those Abused by Priests, a national organization that speaks out against abuse by clergy members.

Now, Serrano says he is liberated by sharing his story and says he hopes he will help others by doing so.

However, he still struggles with the aftermath of the abuse.

"I suffer anxiety attacks today when adults try to build a connection or play with my children. I'm very mistrusting of people in positions of authority, people who have a natural role in my children's lives," Serrano said.

"My parents weren't at fault for my abuse, but it happened on their watch. Surely there were breakdowns. I'm trying to learn from those lessons so my kids are never harmed on my watch."

Normal only on the outside

White, who spoke on condition that her married name not be used, said she was molested by her stepfather starting when she was 4.

"It was such a traumatic thing," said the 45-year-old Riverside woman. "I remember saying that it hurts. He would just ssshhh me and say 'It's OK.' "

She said the abuse always happened at night, when her mother, a waitress, was at work.

"I never made a sound, ever. ... When it was over, he would ... send me to bed. I never said a word, that is how bizarre it is."

The stepfather strongly smelled of cologne, a scent that haunts her still.

"My husband cannot wear a lot of cologne, because I'll gag and I'll physically throw up," she said.

From the outside, White's family seemed ideal, she said. They played cards and board games together at night and went on camping trips.

The older she got, the more aggressive her stepfather became, she said. And as she matured, four other male relatives began to sexually abuse her, she said.

"This is the way life was. I didn't think, 'I have to get out of here.' I never thought, 'This is so weird,' " she said.

"I always told myself, 'I'm never getting married. I'm never having children.' It was so subtle. People would look at me, and I'd be so normal.

"On the outside, I was very normal. On the inside, I felt very dirty, very discarded, very used. I felt very damaged."

White's stepfather died when she was 13. She didn't cry at the funeral.

As she grew older, White said, she could not understand why she had a hard time connecting with people, why she couldn't feel close.

The magnitude of what had happened hit her only after she had children. She went through a severe depression.

"I would just beat myself up. I couldn't tell you what I was upset at. I had a good life. Everything looked so good from the outside. I felt like I couldn't protect my children. I would just sit at the foot of the bed and sob. My energy level was gone. I didn't even know why I was depressed at this point."

She tried to kill herself.

"I felt my family was so much better without me. I didn't understand why I felt damaged until I came to the realization that my family had taken my trust away," she said.

"Forget the physical rape. They literally rape you of your trust, your boundaries, your sense of OK. I think the emotional rape far outweighs the physical."

To this day, she trusts no one with her children. "Do I trust my husband 100 percent? No, I do not.

"I'm still reminding myself to get up every morning ... This is something I have to live with. This is all inward. Nothing you see explains the way I feel."

A split life

Hardeman, of Riverside, said she was 6 years old when a man she trusted first rubbed her back and called her his "little baby girl." He told her he loved her. He bought her pretty dresses and new backpacks.

Her life is divided into two parts: the happy, upper middle-class childhood she remembers before the abuse, and everything else.

The first episode occurred at the home of the man and his wife. Hardeman fell asleep on their couch. She felt somebody place a blanket over her.

"I opened my eyes and it was him," she said. "He smiled and said, 'I don't want you to get cold.' He kissed me on the cheek and said, 'Go back to sleep.' " He pushed her down when she tried to sit up, she said, and told her everything was OK.

"He began touching me ... I was crying the whole time. It freaked me out. He said, 'You don't have to cry.' He said, 'I love you, that's why I'm doing this.' "

The man always smelled of Old Spice.

"To this day, I can't stand it," she said.

She did not tell anyone what had happened, and wouldn't for decades.

"I felt like if I said anything, it was going to be my fault, like I caused it," she said.

Once outgoing, she became withdrawn.

"I don't understand why my parents didn't notice something. I knew I was different," she said. "Every time I would get upset at him, he would say, 'If you tell your daddy, he's going to think you're dirty and he won't love you.' "

When she was 12, she became pregnant. The molester was the father of her child, she said. Her parents never asked who the father was, she said, but forced her to give the baby up for adoption.

She wet the bed until she was 13. She failed gym in junior high and high school, too embarrassed to change in front of other people. She became promiscuous and thought boys didn't care about her if they didn't want sex.

She dropped out of school and ran away from home, searching, she said, for something or someone.

Hardeman said the abuse stopped when she was 17 and became pregnant a second time. She said she does not know whether the second child's father is the molester or a teenage boyfriend. When Hardeman's parents found out she was pregnant again, they sent her to Illinois to live with a relative, she said.

Hardeman said she told no one about the molestation until something her husband did during sex reminded her of her abuse. She said she freaked out and beat her husband until she collapsed sobbing. Then, she told him. She later told her brother and mother. She said her mother dismissed her, telling her it was all in the past. Hardeman has never tried to prosecute her abuser.

Experts say the amount of support a victim gets from family can make all the difference.

"The most important factor in recovery is the degree of support and belief they get from their really closest support system," said David Finkelhor, founder and director of the Crimes Against Children Research Center at the University of New Hampshire.

Finkelhor said how well a child recovers from sexual abuse depends on a number of factors, including whether intercourse and threats occurred, whether the victims had their photographs circulated and whether they have positive psychological resources.

Hardeman said she only recently has come to understand the impact of the abuse.

"It was this one thing that completely changed the way I looked at things in life," she said.

"All those years I was in trouble ... and my parents were disappointed in me, that was all him."

Hardeman said she is now moving on with her life. She recently aced exams to become a long-haul truck driver. She's proud of that accomplishment. Finally, she knows she deserves happiness.

"I know it wasn't my fault. I was 6 years old," she said. "But for many years, I thought it was my fault."

Reach Lisa O'Neill Hill at (909) 368-9462 or loneillhill@...



#104 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Wed Sep 17, 2008 3:40 am
Subject:: Fwd: post traumatic stress
ashutos2
Offline Offline
Send Email Send Email
 
http://www.sciencedaily.com/releases/2007/05/070507183641.htm

Traumatic Events, But Not Post-traumatic Stress Disorder, Common In Childhood

ScienceDaily (May 10, 2007) — Potentially traumatic events are common in children but do not typically result in post-traumatic stress symptoms or disorder, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

 
Post-traumatic stress disorder (PTSD) is a unique psychiatric diagnosis because it requires an initiating event, such as war, rape, natural disaster or serious illness, according to background information in the article. In children, the list of events that could lead to PTSD includes a parent being sent to prison, sudden separation from a loved one and learning of a traumatic event occurring to a loved one.

William E. Copeland, Ph.D., and colleagues at Duke University Medical Center, Durham, N.C., conducted annual interviews with 1,420 children from age 9, 11 or 13 through age 16. Between 1993 and 2000, participants and their parents were interviewed in separate rooms and asked about traumatic events that may have occurred in the previous year. In addition, they reported any symptoms of post-traumatic stress that the children displayed, including compulsive behaviors to suppress memories, panic attacks and engaging in dangerous activities.

More than two-thirds of the children reportedly experienced at least one traumatic event by age 16, including 30.8 with exposure to one event and 37 percent to multiple events. The most common events were witnessing or learning about a trauma that affected others--known as "vicarious" events.

Of those, 13.4 percent of those developed some post-traumatic stress symptoms by age 16, but less than 0.5 percent met the criteria for PTSD. About 9.1 percent experienced painful recall, or distressing memories or images of the traumatic event, and 2.2 percent had a milder, sub-clinical form of PTSD. "Violent or sexual trauma were associated with the highest rates of symptoms," the authors write. "The post-traumatic stress symptoms were predicted by previous exposure to multiple traumas, anxiety disorders and family adversity." In addition, symptoms were more likely to occur among older children.

Children exposed to trauma had nearly double the rates of psychiatric disorders of those who were not (except for substance use disorders). "Across childhood, the children who experience trauma are often those with anxiety, depressive and disruptive behavior disorders, a finding supported in the present study," the authors write. "This likely reflects common liability conveyed from a limited set of family risk factors."

"In the general population of children, potentially traumatic events are fairly common and do not often result in post-traumatic stress symptoms, except after multiple traumas or a history of anxiety," they conclude. "The prognosis after the first lifetime trauma exposure was generally favorable. Apart from PTSD, traumatic events are related to many forms of psychopathology, with the strongest links being with anxiety and depressive disorders."

Article: Arch Gen Psychiatry. 2007;64:577-584.

This study was supported by grants from the National Institute of Mental Health, National Institute on Drug Abuse and the William T. Grant Foundation.


Adapted from materials provided by JAMA and Archives Journals.


#103 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Wed Sep 3, 2008 6:30 am
Subject:: Neurological conditions and streptococoall infection
ashutos2
Offline Offline
Send Email Send Email
 


Hello,
Are mechanisms which cause rheumaic fever with joint and  heart inflammation now implicated in psychological disorders

ashutosh

Childhood and adolescent disorders
Page heading

Further evidence linking streptococcal infections to neuropsychiatric disorders

Coronary-Stent

2 Sep 2008

Researchers have added to the body of evidence linking streptococcal infection to the onset or exacerbation of several neuropsychiatric disorders.

 

Studies have suggested a link between group A b -haemolytic streptococcal (GABHS) infections with the prepubescent onset of obsessive-compulsive disorder (OCD), Tourette syndrome (TS) and tic disorder; however, most of these studies have involved small samples or are based on case reports. Only one large-scale study has been conducted to date which found that patients with new onset OCD, TS or tic disorder were significantly more likely to have had streptococcal infections in the year preceding the onset of the psychiatric illness. Leslie et al. sought to replicate this study using a larger, more nationally representative US sample.

 

They used health insurance claims data to compare the occurrence of streptococcal infection in a sample of privately insured children aged 4–13 years in the year prior to a diagnosis of OCD, TS, tic disorder, attention-deficit/hyperactivity disorder (ADHD), or major depressive disorder (MDD) to that of matched controls. Logistic regression modelling was used to determine the association of prior streptococcal infection of the throat ('strep throat') or scarlet fever with a diagnosis of OCD, TS or tic disorder. The investigation was repeated for infectious diseases otitis media and sinusitis as well as one non-infections condition (migraine).

 

They identified 742 cases of newly diagnosed OCD, TS and tic disorder along with 3,647 controls. Analyses revealed that compared with controls, patients diagnosed with the aforementioned neuropsychiatric disorders were more likely to have had a diagnosis of streptococcal infection in the year preceding diagnosis (odds ratio [OR] 1.54). Furthermore, prior streptococcal infection was also associated with incident diagnoses of ADHD (OR 1.20) and MDD (OR 1.63) among samples of 3,650 cases of newly diagnosed ADHD (18,114 controls), and 341 cases of newly diagnosed MDD (1,710 controls), respectively.

 

No increased occurrence of otitis media or migraine was found before the initial diagnoses of OCD, tic disorders and TS; however, an increased prior occurrence of sinusitis was observed (OR 1.40). "Although we hesitate to read much into this finding, we cannot discount the possibility that it may reflect an increased susceptibility to some but not all infectious diseases in children with these neuropsychiatric disorders and/or the possibility that infection with agents other than GABHS may predispose to this class of disorders," they stated.

 

The authors acknowledged that genetic factors have been implicated in the development of TS, OCD, ADHD and paediatric MDD, stating that infection may serve as a trigger for symptoms in only a subset of genetically susceptible individuals. "It is likely that the aetiology and genetics of these disorders are complex, such that antecedent infections are a causal agent in only a subset of cases," they stated.

 

The authors concluded that their results add to the body of evidence suggesting that an association between streptococcal infections and several neuropsychiatric disorders including OCD, TS, tic disorder, ADHD, and MDD does exist.

 

Reference

Leslie, D. Kozma, L. et al. 2008, 'neuropsychiatric disorders associated with streptococcal infection: A case-control study among privately insured children' Journal of the AmericanAcademy of Child and Adolescent Psychiatry 47: DOI:10.1097/CHI.013e3181825a3d.



#102 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Mon Sep 1, 2008 2:56 pm
Subject:: juices and drugs
ashutos2
Offline Offline
Send Email Send Email
 
 

More Juices Found to Affect Drugs' Effectiveness: Study

http://www.drugs.com/news/more-juices-found-affect-effectiveness-study-13254.html

TUESDAY, Aug. 19 -- Grapefruit juice, long known to boost the absorption of certain medications, isn't the only juice that doesn't mix well with drugs, according to the Canadian researcher who first identified the ill effects of grapefruit juice.

Other common juices, including orange and apple, may limit the body's absorption of drugs, compromising their effectiveness, said David Bailey, a professor of medicine and pharmacology at the University of Western Ontario, in London, Ontario, Canada.

Bailey was expected to present his research Tuesday at the American Chemical Society's national meeting, in Philadelphia.

"The original finding is that [grapefruit juice] markedly boosts the amount of drug that gets into the bloodstream," Bailey said. He first reported that nearly 20 years ago when he discovered that grapefruit juice increased the body's blood levels of the drug felodipine (Plendil), used to treat high blood pressure.

Since the original finding, other researchers have identified dozens of other medications that could interact adversely with grapefruit juice, Bailey said.

Doctors traditionally warn against drinking grapefruit juice if you're taking certain medications for high cholesterol, high blood pressure and heart rhythm problems, according to the American Academy of Family Physicians.

In his latest research, Bailey found that grapefruit juice, as well as orange and apple juice, can lower the body's absorption of some medications. Those drugs include the anti-cancer drugs etoposide (Etopophos, Vepesid); certain beta blockers like tenormin (Atenolol) and talinolol (Cordanum), used to treat high blood pressure and prevent heart attacks; cyclosporine, which is used to prevent organ transplant rejection; and some antibiotics, including ciprofloxacin (Cipro), levofloxacin (Levaquin), and itraconazole (Sporanox).

Bailey also found that healthy volunteers who took the allergy drug fexofenadine (Allegra) with grapefruit juice absorbed only half the amount of the drug, compared with volunteers who took the medicine with water.

In each case, substances in the juices affected the absorption of the drugs. Some chemicals block a drug uptake transporter, reducing drug absorption; other chemicals block a drug metabolizing enzyme that normally breaks down the drugs, he said.

"We don't [yet] know all the drugs affected," Bailey said.

Michael Gaunt is a medication safety analyst at the Institute for Safe Medication Practices in Horsham, Pa. He said, "If this study holds true [in future research], you are going to have to warn people in a similar fashion" about other juices.

Gaunt's advice for now: "In general, it's safest to take medication with water."

Bailey agreed. If you opt for water, he said, "a glass is better than a sip. It helps dissolve the tablet." And cool water is better than hot, he added, because your stomach empties cool water faster, sending the medication on its way to the small intestine and finally the blood stream.

More information

To learn more about juice and medication interactions, visit the American Academy of Family Physicians.


#101 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Mon Aug 18, 2008 2:25 pm
Subject:: Fwd: The Danger of Stress
ashutos2
Offline Offline
Send Email Send Email
 


 

The Danger of Stress

Getting stressed isn't just a state of mind. It can also seriously harm the body.

By Melinda Wenner

 
Email this Article Print this Article    Text Size Graphic Decrease font Enlarge font  
Share
  Review it on NewsTrust    Add to Mixx!  Fark 
 

You probably think you're doing everything you can to stay healthy: you get lots of sleep, exercise regularly and try to avoid fried foods. But you may be forgetting one important thing. Relax! Stress has a bigger impact on your health than you might realize, according to research presented yesterday at the annual conference of the American Psychological Association in Boston.

Ohio State University psychologist Janice Kiecolt-Glaser and her partner, Ronald Glaser, an OSU virologist and immunologist, have spent 20-odd years researching how stress affects the immune system, and they have made some startling discoveries. An easy example comes from their work with caregivers, people who look after chronically ailing spouses or parents (no one would argue that this role is quite stressful). In one experiment, Kiecolt-Glaser and her colleagues administered flu vaccines to caregivers and control subjects and compared the numbers of antibodies—proteins involved in immune reactions—that the two groups produced in response. Only 38 percent of the caregivers produced what is considered an adequate antibody response compared to 66 percent of their relaxed counterparts, suggesting that the caregivers' immune systems weren't doing their jobs very well—and that the stress of caregiving ultimately put them at an increased risk of infection.

If stress affects immune responses, then it should also affect how well the body heals itself. In one particularly cringe-worthy study, Kiecolt-Glaser and her colleagues afflicted a group of caregivers with small arm wounds using a tool dermatologists use to perform skin biopsies. The caregivers' wounds took 24 percent longer to heal than wounds that they had afflicted to non-caregivers.

Okay, but what if caregiving isn't an accurate proxy for stress? To explore other stressful situations, Kiecolt-Glaser and colleagues performed another experiment in which they produced tiny lesions in the mouths of—quite appropriately—11 dental students at two different points in time. Once was during their summer vacation, when they were relaxed, and once was during the fall, several days before a difficult exam. The lesions done before the exam took from two to eight days longer to heal than the summer wounds. For some subjects, the exam wounds took nearly twice as long to get better. Ouch. 

How Stress Hurts

It might seem counterintuitive, but Kiecolt-Glaser believes that stress makes our immune systems less effective because it actually elicits an immune response itself. Stress, she says, causes the body to release pro-inflammatory cytokines, immune factors that initiate responses against infections. When the body produces these cytokines over long periods of time—for instance, as a result of chronic stress—all sorts of bad things can happen. Not only does it hamper our body's ability to fight infection and heal wounds, but chronic inflammation also increases our risk of heart disease, osteoporosis, and autoimmune diseases including type 2 diabetes.

What's more, because regular stress causes a chronic immune response, it can also increase a person's risk for allergies, which occur when the body elicits a chronic immune response against something that's not really dangerous (like pollen). In her most recent study, announced yesterday, Kiecolt-Glaser found that when people are under lots of stress—for instance, when they are forced to deliver a speech or do difficult math problems on the spot—their allergies worsen over the course of the next day.

I admit, this post may not exactly have the intended effect—worrying about the danger of stress is definitely stressful—but take a deep breath. If you ask me, learning a few relaxation techniques sounds like a more appealing illness-prevention strategy than many other alternatives. (Go ahead and throw away that cod liver oil.) Indeed, the next time you feel guilty about enjoying a lazy Sunday, or taking a day off from work for the heck of it, think again. Your body will thank you for it.


PAGE 1  |  2  | Next»


 
.


#100 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Tue Jul 22, 2008 1:02 pm
Subject:: indiatimes chat
ashutos2
Offline Offline
Send Email Send Email
 

Hello,
held today on sexuality and sex education on India times.
.
adessai

#99 From: Rakhee C <rakhee1997@...>
Date:: Sun Jul 20, 2008 8:49 am
Subject:: documentary
rakhee1997@...
Send Email Send Email
 

om sairam


hi to all members

just wanted to know if anyone who is involved in making documentaries topic: special education. you can contact me on my personal id which is rakhee1997@...

Thanks

 
Tough times do not last but tough people do. Have faith in your faith and do not doubt his denials.
Rakhee.S.Chhabria




#98 From: Rakhee C <rakhee1997@...>
Date:: Sun Jul 20, 2008 8:48 am
Subject:: (No subject)
rakhee1997@...
Send Email Send Email
 
hi to all members

just wanted to know if anyone who is involved in making documentaries topic: special education. you can contact me on my personal id which is rakhee1997@...

Thanks

 
Tough times do not last but tough people do. Have faith in your faith and do not doubt his denials.
Rakhee.S.Chhabria



#97 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Wed Jul 16, 2008 5:24 am
Subject:: Fwd: Benefits of early intervention in psychosis not sustained at five years
ashutos2
Offline Offline
Send Email Send Email
 


Benefits of early intervention in psychosis not sustained at five years

11 Jul 2008

 
https://www.omnus.com.au//Psychiatry/ArticleDetails.aspx?articleId={f6fc4977-2b84-4e21-97c0-af0b5c8a1ce8}

Benefits from assertive early intervention in first-episode psychosis are not sustained after patients move to standard care, five-year results from the Danish OPUS program have shown.

A clinical trial randomised 547 patients to standard treatment or to participation in a program that provided assertive community treatment, psychoeducational family treatment, and social skills training.

Intensive treatment was provided for two years. At the end of this period, the OPUS patients had less severe psychotic and negative symptoms, less secondary substance abuse, better treatment adherence, greater success with lower doses of antipsychotics, and higher satisfaction with treatment.

About 56% of patients were available for reassessment five years after the start of the study. There was no difference between OPUS and standard-care patients in the severity of their psychotic or negative symptoms – the primary outcome measures for the study. However, OPUS patients were less likely to be living in supported housing (4% vs 10%) and had spent less total time in hospital (149 vs 193 days). There were no differences in other secondary outcomes at five years, including the prevalence of depression, substance abuse and suicidal behaviour, the use of antipsychotic medication, the proportion who were working or being educated (about 60%) or the proportion in remission.

About 15% in both groups experienced an episodic course of illness, 45% had continuous symptoms, and 40% were not psychotic in the final two years of follow-up.

"Our results give rise to questions about how long early-intervention services should be offered to patients to maintain good clinical and social outcomes," the researchers said. "Second, this trial pinpoints the intrinsic problem of...how to make the transition to normal life as gentle as possible for those patients who no longer need treatment, or who need a less intensive treatment program, while at the same time maintaining continuous treatment for those who develop a chronic course of illness."

More research would be needed to define the optimal duration of intensive intervention, the elements of the treatment package that were most effective, and the characteristics of patients who were most likely to benefit.

Reference
Bertelsen, M. Jeppesen, P. et al. 2008, 'Five-year follow-up of a randomized multicenter trial of intensive early intervention vs standard treatment for patients with a first episode of psychotic illness. The OPUS trial.' Archives of General Psychiatry vol. 65, pp. 762-771.
Abstract

#96 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Jul 13, 2008 6:32 pm
Subject:: Gene discoveries yield autism clues
ashutos2
Offline Offline
Send Email Send Email
 
July 10, 2008 -- Updated 1922 GMT (0322 HKT)
  • Story Highlights
  • Study: Genes suggest autism happens in brains that can't form proper connections
  • Some genes may have been stuck in "off" position, respond to therapy
  • Study reveals wide variety, almost a custom set, of gene defects in each patient
  • Genetic cause is known for only about 15 percent of autism cases

WASHINGTON (AP) -- Harvard researchers have discovered half a dozen new genes involved in autism that suggest the disorder strikes in a brain that can't properly form new connections.

Gene discoveries yield autism clues

The findings also may help explain why intense education programs do help some autistic children -- because certain genes that respond to experience weren't missing, they were just stuck in the "off" position.

"The circuits are there but you have to give it an extra push," said Dr. Gary Goldstein of the Kennedy Krieger Institute in Baltimore, Maryland, which wasn't involved in the gene hunt but is well-known for its autism behavioral therapy.

The genetics suggest that "what we're doing makes sense when we work with these little kids -- and work and work and work -- and suddenly get through," he said.

But the study's bigger message is that autism is too strikingly individual to envision an easy gene test for it. Instead, patients are turning out to have a wide variety, almost a custom set, of gene defects.

"Almost every kid with autism has their own particular cause of it," said Dr. Christopher Walsh, chief of genetics at Children's Hospital Boston, Massachusetts, who led the research published in Friday's edition of the journal Science.

Autism spectrum disorders include a range of poorly understood brain conditions, from the mild Asperger's syndrome to more severe autism characterized by poor social interaction, impaired communication and repetitious behaviors.

It's clear that genes play a big role in autism, from studies of twins and families with multiple affected children. But so far, the genetic cause is known for only about 15 percent of autism cases, Walsh said.

So Walsh's team took a new tack. They turned to the Middle East, a part of the world with large families and a tendency for cousins to marry, characteristics that increase the odds of finding rare genes. They recruited 88 families with cousin marriages and a high incidence of autism, from Jordan, Saudi Arabia, Kuwait, Oman, Pakistan, Qatar, Turkey and the United Arab Emirates. They compared the DNA of family members to search for what are called recessive mutations -- where mom and dad can be healthy carriers of a gene defect but a child who inherits that defect from both parents gets sick.

In some of the families, they found large chunks of missing DNA regions that followed that recessive rule. The missing regions varied among families, but they affected at least six genes that play a role in autism.

Here's why this matters: All the genes seem to be part of a network involved in a basic foundation of learning -- how neurons respond to new experiences by forming connections between each other, called synapses.

In the first year or two of life -- when autism symptoms appear _ synapses rapidly form and mature, and unnecessary ones are "pruned" back. In other words, a baby's brain is literally being shaped by its first experiences so that it is structurally able to perform learning and other functions of later life.

"This paper points to problems specifically in the way that experience sculpts the developing brain," explained Dr. Thomas Insel, director of the National Institute of Mental Health, which helped fund the work.

Some earlier research had pointed to the same underlying problem, so these newly found genes "join a growing list to suggest that autism is a synaptic disorder," he said.

If that sounds discouraging, here's the good news: The missing DNA didn't always translate into missing genes. Instead what usually was missing were the on/off switches for these autism-related genes. Essentially, some genes were asleep instead of doing their synapse work.

"I find that hopeful" because "there are ways that are being discovered to activate genes," Walsh said. "This might be an unanticipated way of developing therapies in the long term for autism: Identifying these kids where all the right genes are present, just not turned on in the right way."

At Kennedy Krieger, Goldstein thinks the work may provide a gene-level explanation for why some children already are helped by intense therapy.

"We have trouble getting through to these children, but with repeated stimulation we can do it," he said. "These are circuits that have an ability not so much to recover but to work around the problem."


#95 From: "Ashutosh Prabhu Dessai" <ashutosh.prabhudessai@...>
Date:: Sun Jul 13, 2008 2:17 pm
Subject:: pet industry
ashutos2
Offline Offline
Send Email Send Email
 
The practice of prescribing medications designed for humans to animals
has grown substantially over the past decade and a half, and
pharmaceutical companies have recently begun experimenting with a more
direct strategy: marketing behavior-modification and "lifestyle" drugs
specifically for pets. America's animals, it seems, have very American
health problems. Dogs in USA live 13 years on average, considerably longer than
they did in the past; Pfizer's Anipryl treats cognitive dysfunction so
that absent-minded pets can remember the location of the supper bowl or
doggy door. For lonely dogs with separation anxiety, Eli Lily brought to market its own drug Reconcile last year. The only difference between it and Prozac is that Reconcile is chewable and tastes like beef. Marketers have a new name for the age-old tendency to view animals as
furry versions of ourselves: "humanization," a trend that is fueling
the explosive growth of the pet industry and the rise of modern pet
pharma. Americans forked over $49 billion for pet products and services
last year, up $11.5 billion from 2003; other than consumer electronics,
pet products are the fastest-growing retail segment. Humanization has pharmaceutical companies salivating like Pavlov's dogs.
Not very surprising...eh?!
Read the full story at: http://www.nytimes.com/2008/07/13/magazine/13pets-t.html?ref=magazine


Messages 95 - 124 of 127   Newest  |  < Newer  |  Older >  |  Oldest
Advanced

Copyright © 2009 Yahoo! Inc. All rights reserved.
Privacy Policy - Terms of Service - Guidelines - Help