Toxicological studies on ratanjyot oil.

The oil caused severe diarrhoea and gastro-intestinal inflammation.
The isolated toxic fraction, when applied to the skin of rabbits and
rats, produced a severely irritant reaction followed by necrosis; in
mice, this fraction had a dermally toxic and lethal effect. The oil
and the toxic fraction at 25 and 1 mg respectively in 10 ml saline
showed haemolytic activity, disrupting red blood cells. Detoxification
or complete removal of the potent toxins present in ratanjyot oil is
essential before its use in industrial applications or in human
medicine can be considered.

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